Schumer M, Miller-Crain G, Pfeifer M A
University of Louisville Department of Medicine, Kentucky.
Am J Med. 1988 Nov 28;85(5A):144-6. doi: 10.1016/0002-9343(88)90407-x.
To confirm the reliability and validity of cardiovascular autonomic nervous system tests, RR-variation and Valsalva maneuver, coefficient of variation for triplicate tests was calculated. The testing data were collected from patients participating in the Statil Neuropathy Trial. Triplicate testing was done within a three-week period at three different time points: baseline, 12 months, and 18 months. BMDP Statistical Software was used in the analysis. There is no significant difference between the coefficients of variation between clinics for either RR-variation or Valsalva maneuver tests. The coefficient of variation of pooled data was not significantly different from the coefficient of variation of individual clinics. Furthermore, there was no evidence that there was a significant worsening of coefficient of variation with time. Thus, RR-variation and Valsalva maneuver provide reliable and reproducible results that do not vary in consistency over time.
为了确认心血管自主神经系统测试、RR 变异性和瓦尔萨尔瓦动作的可靠性和有效性，计算了三次测试的变异系数。测试数据收集自参与 Statil 神经病变试验的患者。在三周内的三个不同时间点（基线、12 个月和 18 个月）进行了三次测试。分析使用了 BMDP 统计软件。RR 变异性或瓦尔萨尔瓦动作测试在各诊所之间的变异系数没有显著差异。汇总数据的变异系数与各诊所的变异系数没有显著差异。此外，没有证据表明变异系数会随时间显著恶化。因此，RR 变异性和瓦尔萨尔瓦动作提供了可靠且可重复的结果，其一致性不会随时间而变化。
