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关于在非无菌搅拌流化床生物反应器中真菌菌群对药物及其代谢物降解情况的数据。

Data on the degradation of pharmaceuticals and their metabolites by a fungal consortium in a non-sterile stirred fluidized bioreactor.

作者信息

Kasonga Teddy Kabeya, Coetzee Martie A A, Kamika Ilunga, Momba Maggy Ndombo Benteke

机构信息

Department of Environmental, Water and Earth Sciences, Faculty of Sciences, Tshwane University of Technology, P/B X 680, Pretoria, 0001, South Africa.

Department of Environmental Sciences, Faculty of Sciences, University of South Africa, South Africa.

出版信息

Data Brief. 2019 Dec 31;28:105057. doi: 10.1016/j.dib.2019.105057. eCollection 2020 Feb.

Abstract

Pharmaceutical compounds (PhCs) are widely prevalent environmental contaminants, with recalcitrant behaviour to conventional biodegradation processes and harmful effects to the ecosystem and human health. Hence, developing an eco-friendly cost-effective process exploring the microbial agents appeared to be promising for the treatment of PhC contaminated effluents. A consortium of the previously isolated and identified South African indigenous fungal strains, namely , , , and was used in a non-sterile stirred fluidized bioreactor (NSFB) to perform the simultaneous biodegradation of selected PhCs. The degradation of the PhCs, namely carbamazepine (CBZ), diclofenac (DCF) and ibuprofen (IBP) as well as their transformation metabolite compounds was carried out using the SPE-UPLC/MS. Here are presented data with regard to the NSFB design, the effect of the concentration of carbon source on the growth of a fungal consortium in the NSFB, the fungal mycelial morphology, and the assessment of the physicochemical parameters. The data displayed the stoichiometric reactions of the transformation fragments and their mass spectrum. For better understanding of the data presented in the present paper, please refer to the original paper "Degradation of pharmaceuticals and their metabolites in non-sterile stirred fluidized bioreactor driven by a fungal consortium" [1].

摘要

药物化合物(PhCs)是广泛存在的环境污染物,对传统生物降解过程具有顽固性,对生态系统和人类健康有有害影响。因此,开发一种探索微生物制剂的环保且经济高效的工艺,对于处理受PhC污染的废水似乎很有前景。使用先前分离和鉴定的南非本土真菌菌株组成的联合体,即 、 、 、 和 ,在非无菌搅拌流化床生物反应器(NSFB)中对选定的PhCs进行同步生物降解。使用固相萃取-超高效液相色谱/质谱联用仪(SPE-UPLC/MS)对PhCs,即卡马西平(CBZ)、双氯芬酸(DCF)和布洛芬(IBP)及其转化代谢产物进行降解。本文介绍了有关NSFB设计、碳源浓度对NSFB中真菌联合体生长的影响、真菌菌丝形态以及理化参数评估的数据。数据展示了转化片段的化学计量反应及其质谱图。为了更好地理解本文所呈现的数据,请参考原始论文《真菌联合体驱动的非无菌搅拌流化床生物反应器中药物及其代谢产物的降解》[1]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e13e/6957873/7782ad801ff6/gr1.jpg

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