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电子烟使用尝试是否会增加法国年轻曾吸烟者向每日吸烟的转变?

Does e-cigarette experimentation increase the transition to daily smoking among young ever-smokers in France?

机构信息

Université Paris-Sud, Université Paris-Saclay, faculté de médecine, faculté de médecine UVSQ, Inserm, CESP, 92541, Villejuif, France; Observatoire français des drogues et des toxicomanies (OFDT), 69, rue de Varenne, 75007, Paris, France.

Department of Family Medicine and Public Health, University of California, San Diego, 9500 Gilman Drive, La Jolla, 92093, CA, USA; Scripps Institution of Oceanography, University of California, San Diego, CA, USA.

出版信息

Drug Alcohol Depend. 2020 Mar 1;208:107853. doi: 10.1016/j.drugalcdep.2020.107853. Epub 2020 Jan 11.

Abstract

INTRODUCTION

According to multiple studies, e-cigarette use among adolescents is associated with subsequent smoking initiation. However, little is known about its effect on the transition from smoking initiation to daily smoking.

METHODS

Using retrospective data from a French national representative survey collected in 2017 (n = 39,115), we analyzed the role of ever using e-cigarettes on daily cigarette smoking status at 17 among ever smokers (n = 21,401). Risk-ratios (RR) were computed through modified Poisson regressions with an inverse probability of treatment weighting (IPTW) approach.

RESULTS

Among French adolescents aged 17, 16.8 % declared current e-cigarette use (1.9 % reported daily use) and 34.1 % cigarette smoking (25.1 % reported daily smoking). Among ever-smokers, adolescents who declared having ever used e-cigarettes were less likely than those who did not to transition to daily smoking at 17: RR = 0.62 95 %CI [0.60 - 0.64]. We found similar results for those who experimented with e-cigarettes before initiating smoking, RR = 0.76 95 %CI [0.66 - 0.89].

CONCLUSIONS

Our results found no evidence of an increased risk of transitioning to daily smoking at 17 among ever-smokers who also experimented with e-cigarettes. Further studies should investigate the longer-term role of vaping on future smoking habits with the use of causal inference methods.

摘要

引言

多项研究表明,青少年使用电子烟与随后的吸烟起始有关。然而,对于电子烟对吸烟起始向每日吸烟的转变的影响,知之甚少。

方法

利用 2017 年进行的一项法国全国代表性调查的回顾性数据(n=39115),我们分析了曾经吸烟者(n=21401)中曾经使用电子烟对 17 岁时每日吸烟状况的作用。通过使用逆概率治疗加权(IPTW)方法的改良泊松回归计算风险比(RR)。

结果

在法国 17 岁的青少年中,16.8%报告目前使用电子烟(1.9%报告每日使用),34.1%报告吸烟(25.1%报告每日吸烟)。在曾经吸烟者中,与未使用电子烟的人相比,报告曾经使用过电子烟的青少年更不可能在 17 岁时过渡到每日吸烟:RR=0.62[95%CI:0.60-0.64]。对于那些在开始吸烟前尝试过电子烟的人,我们也得到了类似的结果,RR=0.76[95%CI:0.66-0.89]。

结论

我们的研究结果未发现曾经吸烟者同时尝试电子烟与 17 岁时过渡到每日吸烟的风险增加有关。需要进一步的研究,使用因果推理方法来调查电子烟在未来吸烟习惯方面的长期作用。

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