Department of Psychiatry & Behavioral Sciences, Duke University School of Medicine, Box 102848, Durham, NC, 27705, USA.
AIDS Behav. 2020 Aug;24(8):2336-2346. doi: 10.1007/s10461-020-02793-6.
Stimulant abuse is a major contributor to HIV transmission in the United States, yet HIV prevalence among persons who use illicit stimulants remains unknown. We implemented respondent driven sampling (RDS) to estimate the prevalence of HIV infection in this high-risk population. We also examined RDS-adjusted rates of risk behaviors among HIV-positive and HIV-negative participants. Recruited from seven seeds, our sample of 387 participants was 46% female, 89% African American, and 45.94 years old on average. Participants were predominantly non-injection cocaine users, had large networks of stimulant users, and reported an established relationship with their recruiter. The adjusted population proportion of HIV infection was 0.07 (0.04, 0.11). The majority of sexually active participants reported engagement in risk behaviors (73%), but rates generally did not differ by HIV status. Our results highlight that stimulant use is a risk factor for HIV infection. This study also demonstrates that RDS is a very effective strategy for reaching stimulant users in the community.
兴奋剂滥用是美国 HIV 传播的主要因素，但使用非法兴奋剂者中的 HIV 流行率尚不清楚。我们实施了应答者驱动抽样 (RDS) 来估计这一高危人群的 HIV 感染流行率。我们还检查了 HIV 阳性和 HIV 阴性参与者中经 RDS 调整的风险行为率。我们的样本由 387 名参与者组成，来自七个种子，其中 46%为女性，89%为非裔美国人，平均年龄为 45.94 岁。参与者主要是非注射可卡因使用者，拥有庞大的兴奋剂使用者网络，并与他们的招募者建立了稳定的关系。调整后的人群 HIV 感染率为 0.07（0.04，0.11）。大多数有性行为的参与者报告参与了风险行为（73%），但 HIV 状况通常没有差异。我们的研究结果强调了兴奋剂使用是 HIV 感染的一个风险因素。本研究还表明，RDS 是在社区中接触兴奋剂使用者的一种非常有效的策略。
