Green Lauren, Cook Laurie, Martinez Margaret, Green Eric
From the Veterinary Medical Center, and Department of Veterinary Clinical Services (L.G., L.C., E.G.), and Department of Veterinary Biosciences (M.M.), College of Veterinary Medicine, The Ohio State University, Columbus, Ohio.
J Am Anim Hosp Assoc. 2020 Mar/Apr;56(2):127-132. doi: 10.5326/JAAHA-MS-6736. Epub 2020 Jan 21.
A 4 mo old spayed female mixed-breed dog was presented for focal lower motor neuron signs of the right forelimb and marked hyperesthesia on axillary palpation. Her signs progressed rapidly over the following days to diffuse lower motor neuron signs in all limbs and a seizure. MRI demonstrated a focal, slightly right-sided, 2.5 cm region of noncontrast-enhancing T2 hyperintensity and T1 isointensity at C4-C5 spinal cord segments. Imaging of the brain was unremarkable. The dog was euthanized as a result of poor prognosis. Polymerase chain reaction on cerebrospinal fluid and immunohistochemistry of brain tissue were both positive for canine distemper virus. This report documents an atypical presentation of canine distemper encephalomyelitis causing lower motor neuron signs and hyperesthesia.
一只4月龄已绝育的雌性混血犬因右前肢局灶性下运动神经元体征以及腋窝触诊时明显的感觉过敏前来就诊。在接下来的几天里，其症状迅速发展为四肢弥漫性下运动神经元体征并伴有癫痫发作。磁共振成像（MRI）显示在C4 - C5脊髓节段有一个局灶性、略偏向右侧的2.5厘米区域，T2加权像呈高信号且T1加权像呈等信号，无强化表现。脑部成像未见异常。由于预后不良，该犬实施了安乐死。脑脊液聚合酶链反应和脑组织免疫组化检测均显示犬瘟热病毒呈阳性。本报告记录了一例引起下运动神经元体征和感觉过敏的犬瘟热脑脊髓炎的非典型表现。
