Wang Lu-Liang, Yang Cheng-Xiong, Yan Xiu-Ping
College of Chemistry, Research Center for Analytical Sciences, Tianjin Key Laboratory of Molecular Recognition and Biosensing, State Key Laboratory of Medicinal Chemical Biology, Nankai University, 94 Weijin Road, Tianjin, 300071, China.
Collaborative Innovation Center of Chemical Science and Engineering, 94 Weijin Road, Tianjin, 300071, China.
Chempluschem. 2017 Jun;82(6):933-938. doi: 10.1002/cplu.201700223.
A facile, in situ growth strategy for the synthesis of monodispersed COF@SiO microspheres is reported. The microspheres have uniform and controllable COF shells, and are used as the stationary phase for HPLC. The TpBD COF, constructed from 1,3,5-triformylphloroglucinol (Tp) and benzidine (BD), is taken as the COF shell, and aminosilica (SiO -NH ) is employed as the core to support the TpBD shell. The TpBD shell thickness is adjusted by controlling the concentrations of the Tp and BD monomers. The TpBD@SiO packed columns show excellent hydrophobic selectivity, and good reproducibility for the separation of neutral (toluene and ethylbenzene, polycyclic aromatic hydrocarbons), acidic (hydroquinone, p-cresol, and p-chlorophenol), and basic molecules (nucleobases, nucleosides, and deoxynucleosides).
报道了一种用于合成单分散COF@SiO微球的简便原位生长策略。这些微球具有均匀且可控的COF壳层，并用作高效液相色谱的固定相。由1,3,5-三(甲酰基)间苯三酚(Tp)和联苯胺(BD)构建的TpBD COF用作COF壳层，氨基二氧化硅(SiO -NH )用作核心来支撑TpBD壳层。通过控制Tp和BD单体的浓度来调节TpBD壳层的厚度。TpBD@SiO填充柱在分离中性分子(甲苯和乙苯、多环芳烃)、酸性分子(对苯二酚、对甲酚和对氯苯酚)和碱性分子(核碱基、核苷和脱氧核苷)方面表现出优异的疏水选择性和良好的重现性。
