• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

一名新发高血压和低钾血症患者的分泌肾素的卵巢成人颗粒细胞瘤

RENIN-SECRETING OVARIAN ADULT GRANULOSA CELL TUMOR IN A PATIENT WITH NEW-ONSET HYPERTENSION AND HYPOKALEMIA.

作者信息

Karaman Rowan, Xu Jin, Harrison Ross F, Kushner David M, Weisman Paul S, Shenker Yoram

出版信息

AACE Clin Case Rep. 2018 Nov 1;5(2):e168-e171. doi: 10.4158/ACCR-2018-0355. eCollection 2019 Mar-Apr.

DOI:10.4158/ACCR-2018-0355
PMID:31967026
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6873859/
Abstract

OBJECTIVE

To describe a case of a renin-secreting ovarian tumor, which is a rare cause of hyperreninemia leading to secondary hypertension and hypokalemia.

METHODS

We present the first case of a patient with a molecularly confirmed renin-secreting ovarian adult granulosa cell tumor.

RESULTS

A 31-year-old female presented with hypertension and amenorrhea. She was found to have spontaneous hypokalemia. Computed tomography scan showed a pelvic mass which was resected and found to be a renin-secreting ovarian adult granulosa cell tumor. The hypertension and hypokalemia resolved after the mass was resected.

CONCLUSION

Renin-secreting ovarian adult granulosa cell tumors are rare causes of hyperreninemia leading to hypertension and hypokalemia.

摘要

目的

描述一例分泌肾素的卵巢肿瘤，这是导致继发性高血压和低钾血症的高肾素血症的罕见病因。

方法

我们报告首例经分子学确诊的分泌肾素的卵巢成人颗粒细胞瘤患者。

结果

一名31岁女性出现高血压和闭经。发现她有自发性低钾血症。计算机断层扫描显示盆腔有一肿块，切除后发现是分泌肾素的卵巢成人颗粒细胞瘤。肿块切除后，高血压和低钾血症得以缓解。

结论

分泌肾素的卵巢成人颗粒细胞瘤是导致高血压和低钾血症的高肾素血症的罕见病因。

相似文献

1
RENIN-SECRETING OVARIAN ADULT GRANULOSA CELL TUMOR IN A PATIENT WITH NEW-ONSET HYPERTENSION AND HYPOKALEMIA.一名新发高血压和低钾血症患者的分泌肾素的卵巢成人颗粒细胞瘤
AACE Clin Case Rep. 2018 Nov 1;5(2):e168-e171. doi: 10.4158/ACCR-2018-0355. eCollection 2019 Mar-Apr.
2
Renin-producing ovarian tumor. A case report with immunohistochemical and electron-microscopic study.
Am J Surg Pathol. 1988 Aug;12(8):634-40.
3
Extrarenal renin-secreting tumors: insights into hypertension and ovarian renin production.
Medicine (Baltimore). 1989 Sep;68(5):257-68. doi: 10.1097/00005792-198909000-00001.
4
A case of ectopic renin-secreting orbital hemangiopericytoma associated with juvenile hypertension and hypokalemia.一例与青少年高血压和低钾血症相关的异位分泌肾素的眼眶血管外皮细胞瘤。
Acta Med Okayama. 1979 Aug;33(4):315-22.
5
Secondary hypertension due to a renin-secreting juxtaglomerular cell tumor.由于分泌肾素的肾小球旁细胞肿瘤引起的继发性高血压。
J Formos Med Assoc. 2010 Mar;109(3):237-40. doi: 10.1016/S0929-6646(10)60047-2.
6
Renin-producing serous cystoadenocarcinoma of the ovary: a case report.
Eur J Gynaecol Oncol. 2002;23(3):183-6.
7
Renin-secreting tumors.肾素分泌瘤
J Okla State Med Assoc. 1990 Feb;83(2):57-9.
8
Secondary hypertension due to a renin-producing teratoma.由产生肾素的畸胎瘤引起的继发性高血压。
Am J Hypertens. 2003 Jul;16(7):592-5. doi: 10.1016/s0895-7061(03)00865-3.
9
Secondary Amenorrhea and Infertility Due to an Inhibin B Producing Granulosa Cell Tumor of the Ovary. A Rare Case Report and Literature Review.因卵巢产生抑制素 B 的颗粒细胞瘤导致的继发性闭经和不孕。罕见病例报告及文献复习。
Medicina (Kaunas). 2021 Aug 17;57(8):829. doi: 10.3390/medicina57080829.
10
Refractory hypertension and isosexual pseudoprecocious puberty associated with renin-secreting ovarian steroid cell tumor in a girl.女孩的肾素分泌性卵巢类固醇细胞瘤与难治性高血压和同性假性性早熟相关。
J Korean Med Sci. 2011 Jun;26(6):836-8. doi: 10.3346/jkms.2011.26.6.836. Epub 2011 May 18.

引用本文的文献

1
Rare case of steroid cell tumour presenting as resistant hypertension in early pregnancy.罕见类固醇细胞瘤病例在孕早期表现为耐药性高血压。
BMJ Case Rep. 2023 Dec 20;16(12):e255716. doi: 10.1136/bcr-2023-255716.

本文引用的文献

1
The Ovarian Renin-Angiotensin System (OVRAS): A Major Factor in Ovarian Function and Disease.卵巢肾素-血管紧张素系统（OVRAS）：卵巢功能与疾病的主要因素
Reprod Sci. 2016 Dec;23(12):1644-1655. doi: 10.1177/1933719116672588.
2
FOXL2 molecular status in adult granulosa cell tumors of the ovary: A study of primary and metastatic cases.卵巢成人颗粒细胞瘤中的FOXL2分子状态：原发性和转移性病例研究
Oncol Lett. 2016 Aug;12(2):1159-1163. doi: 10.3892/ol.2016.4711. Epub 2016 Jun 14.
3
Is there a role of the local tissue RAS in the regulation of physiologic and pathophysiologic conditions in the reproductive tract?局部组织肾素-血管紧张素系统（RAS）在生殖道的生理和病理生理条件调节中是否起作用？
J Renin Angiotensin Aldosterone Syst. 2011 Dec;12(4):385-93. doi: 10.1177/1470320311418140. Epub 2011 Aug 8.
4
Refractory hypertension and isosexual pseudoprecocious puberty associated with renin-secreting ovarian steroid cell tumor in a girl.女孩的肾素分泌性卵巢类固醇细胞瘤与难治性高血压和同性假性性早熟相关。
J Korean Med Sci. 2011 Jun;26(6):836-8. doi: 10.3346/jkms.2011.26.6.836. Epub 2011 May 18.
5
Role of the renin-angiotensin system in gynecologic cancers.肾素-血管紧张素系统在妇科癌症中的作用。
Curr Cancer Drug Targets. 2011 May;11(4):405-11. doi: 10.2174/156800911795538057.
6
FOXL2 is a sensitive and specific marker for sex cord-stromal tumors of the ovary.FOXL2 是卵巢性索-间质肿瘤的一个敏感且特异的标志物。
Am J Surg Pathol. 2011 Apr;35(4):484-94. doi: 10.1097/PAS.0b013e31820a406c.
7
Mutation of FOXL2 in granulosa-cell tumors of the ovary.卵巢颗粒细胞瘤中FOXL2的突变
N Engl J Med. 2009 Jun 25;360(26):2719-29. doi: 10.1056/NEJMoa0902542. Epub 2009 Jun 10.
8
Arterial hypertension and ovarian tumour in a girl: what is the link?
Nephrol Dial Transplant. 2005 Jan;20(1):231-4. doi: 10.1093/ndt/gfh477. Epub 2004 Aug 24.
9
Renin-producing ovarian tumor. A case report with immunohistochemical and electron-microscopic study.
Am J Surg Pathol. 1988 Aug;12(8):634-40.