Roswell R H
Veterans Administration Medical Center, Oklahoma City, OK.
J Okla State Med Assoc. 1990 Feb;83(2):57-9.
Hypertension resulting from a renin-secreting tumor was first reported in 1967 by Robertson et al. Kihara and coworkers subsequently coined the term juxtaglomerular cell tumor for a similar tumor in a young woman with hyperreninemic hypertension. Since the description of these first two cases, it has become clear that renin-secreting tumors of both renal and nonrenal origin can cause surgically curable hypertension. Primary reninism has been suggested as a more appropriate term for the clinical syndrome associated with renin-secreting tumors, both renal and extrarenal, whether benign or malignant.
1967年，罗伯逊等人首次报告了由分泌肾素的肿瘤引起的高血压。木原及其同事随后为一名患有高肾素血症性高血压的年轻女性身上的类似肿瘤创造了“肾小球旁细胞瘤”一词。自从这前两例病例被描述以来，已经很清楚，肾源性和非肾源性分泌肾素的肿瘤均可导致可通过手术治愈的高血压。有人提出“原发性肾素增多症”是一个更合适的术语，用于描述与分泌肾素的肿瘤（包括肾内和肾外的，无论良性还是恶性）相关的临床综合征。
