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晚年的社交参与可能会减轻因童年时期经济压力而产生的抑郁症状负担。

Social engagement in late life may attenuate the burden of depressive symptoms due to financial strain in childhood.

机构信息

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden; Division of Geriatric Medicine, Department di Biomedical, Metabolic e Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

出版信息

J Affect Disord. 2020 Feb 15;263:336-343. doi: 10.1016/j.jad.2019.11.163. Epub 2019 Dec 2.

Abstract

BACKGROUND

It remains poorly understood if childhood financial strain is associated with old-age depression and if active social life may mitigate this relationship.

AIMS

To investigate the association between childhood financial strain and depressive symptoms during aging; to examine whether late-life social engagement modifies this association.

METHOD

2884 dementia-free individuals (aged 60+) from the Swedish National study of Aging and Care-Kungsholmen were clinically examined over a 15-year follow-up. Presence of childhood financial strain was ascertained at baseline. Depressive symptoms were repeatedly assessed with the Montgomery-Åsberg Depression Rating Scale. Social engagement comprised information on baseline social network and leisure activities. Linear, logistic and mixed-effect models estimated baseline and longitudinal associations accounting for sociodemographic, clinical, and lifestyle factors.

RESULTS

Childhood financial strain was independently associated with a higher baseline level of depressive symptoms (β = 0.37, 95%CI 0.10-0.65), but not with symptom change over time. Relative to those without financial strain and with active social engagement, depressive burden was increased in those without financial strain but with inactive social engagement (β = 0.43, 95%CI: 0.15-0.71), and in those with both financial strain and inactive engagement (β = 0.99, 95%CI: 0.59-1.40). Individuals with financial strain and active social engagement exhibited similar depressive burden as those without financial strain and with active social engagement.

LIMITATIONS

Recall bias and reverse causality may affect study results, although sensitivity analyses suggest their limited effect.

CONCLUSIONS

Early-life financial strain may be of lasting importance for old-age depressive symptoms. Active social engagement in late-life may mitigate this association.

摘要

背景

儿童时期的经济压力是否与老年期抑郁有关,以及积极的社交生活是否可能减轻这种关系,目前仍知之甚少。

目的

探讨儿童时期的经济压力与老年期抑郁症状之间的关系;研究晚年社交参与是否会改变这种关系。

方法

2884 名无痴呆症的个体(年龄在 60 岁以上)来自瑞典国家衰老和护理- Kungsholmen 研究,在 15 年的随访中进行了临床检查。在基线时确定儿童时期经济压力的存在。使用蒙哥马利-Åsberg 抑郁评定量表(Montgomery-Åsberg Depression Rating Scale)反复评估抑郁症状。社交参与包括基线社交网络和休闲活动的信息。线性、逻辑回归和混合效应模型估计了考虑社会人口统计学、临床和生活方式因素的基线和纵向关联。

结果

儿童时期的经济压力与较高的基线抑郁症状水平独立相关(β=0.37,95%CI 0.10-0.65),但与随时间的症状变化无关。与没有经济压力且社交活跃的人相比,没有经济压力但社交不活跃的人抑郁负担增加(β=0.43,95%CI:0.15-0.71),而那些同时存在经济压力和社交不活跃的人抑郁负担增加更明显(β=0.99,95%CI:0.59-1.40)。有经济压力但社交活跃的个体与没有经济压力但社交活跃的个体具有相似的抑郁负担。

局限性

回忆偏倚和反向因果关系可能会影响研究结果,尽管敏感性分析表明其影响有限。

结论

儿童时期的经济压力可能对老年期的抑郁症状具有持久的重要性。晚年积极的社交参与可能会减轻这种关联。

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