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苏丹喀土穆州喀土穆辐射与同位素中心白血病患儿的口腔健康状况及其决定因素。

Oral health status and its determinants in children with leukaemia at the Radiation and Isotope Center Khartoum, Khartoum State, Sudan.

作者信息

Ali Moataz Hassan Mohammed, Nurelhuda Nazik Mostafa

机构信息

Pediatric Dentistry Department.

Dental Public Health Unit, Faculty of Dentistry, University of Khartoum, Sudan.

出版信息

Sudan J Paediatr. 2019;19(2):93-100. doi: 10.24911/SJP.106-1568288518.

DOI:10.24911/SJP.106-1568288518
PMID:31969737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6962270/
Abstract

The burden of oral health diseases in children with leukaemia and the impact of cancer treatment on their oral health have not been studied in Sudan. The present study assesses the oral health status of leukemic children through measuring caries experience, gingival status, oral hygiene status and mucositis. It also explores the association between the oral health status of children with leukaemia and their parental education, oral hygiene habits, treatment stage and type of leukaemia. A cross sectional hospital-based study was conducted at the Radiation and Isotope Center Khartoum, Khartoum State. A total of 87 children were included in this study. Data were collected by interviewer questionnaire and clinical examination. The oral health status revealed high prevalence of untreated dental caries (37.9%) and the majority (67.9%) of children had poor oral hygiene. Nearly, all children with leukaemia (93.1%) had never visited a dental health facility in their lives. Regarding the treatment stages of leukaemia, the severity of dental caries was found to be more significant in the maintenance phase, while oral mucositis was more significant in the induction phase.

摘要

在苏丹,尚未对白血病患儿的口腔健康疾病负担以及癌症治疗对其口腔健康的影响进行研究。本研究通过测量龋齿经历、牙龈状况、口腔卫生状况和口腔黏膜炎来评估白血病患儿的口腔健康状况。它还探讨了白血病患儿的口腔健康状况与其父母教育程度、口腔卫生习惯、治疗阶段和白血病类型之间的关联。在喀土穆州喀土穆的辐射与同位素中心进行了一项基于医院的横断面研究。本研究共纳入了87名儿童。通过访谈问卷和临床检查收集数据。口腔健康状况显示,未经治疗的龋齿患病率很高(37.9%),大多数儿童(67.9%)口腔卫生较差。几乎所有白血病患儿(93.1%)一生中从未去过牙科保健机构。关于白血病的治疗阶段,发现龋齿的严重程度在维持期更为显著,而口腔黏膜炎在诱导期更为显著。

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本文引用的文献

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Prevalence of oral manifestations in children and adolescents with cancer submitted to chemotherapy.接受化疗的癌症儿童和青少年口腔表现的患病率。
BMC Oral Health. 2016 Oct 3;16(1):107. doi: 10.1186/s12903-016-0300-2.
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Dental Awareness among Parents and Oral Health of Paediatric Cancer Patients Receiving Chemotherapy.接受化疗的儿科癌症患者父母的牙齿保健意识与口腔健康
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Relationship between oral health status and hematological values in pediatric leukemic patients: an evaluative survey.儿科白血病患者口腔健康状况与血液学指标的关系:一项评估性调查。
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Oral health status of children with acute lymphoblastic leukemia undergoing chemotherapy.接受化疗的急性淋巴细胞白血病患儿的口腔健康状况
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Pretherapeutic plasma pro- and anti- inflammatory mediators are related to high risk of oral mucositis in pediatric patients with acute leukemia: a prospective cohort study.治疗前血浆促炎和抗炎介质与儿童急性白血病患者口腔黏膜炎的高风险相关:一项前瞻性队列研究。
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