Universidade Potiguar, NatalRN, Brasil, Odontologia, Universidade Potiguar, Natal, RN, Brasil.
Liga Norte-Riograndense Contra o Câncer, NatalRN, Brasil, Liga Norte-Riograndense Contra o Câncer, Natal, RN, Brasil.
Braz J Otorhinolaryngol. 2014 Jan-Feb;80(1):78-85. doi: 10.5935/1808-8694.20140015.
Acute lymphocytic leukemia is a type of cancer most common in children and it is characterized by excessive and disordered immature leukocytes in the bone marrow.
Identify most frequent oral manifestations in children with acute lymphocytic leukemia under chemotherapy treatment.
The research was conducted on the electronic database PubMed/Medline, Science Direct, Scielo and Scopus. It has been sought papers with full presentation, wrote in Portuguese, English and Spanish, published between January 1992 and April 2013.
From studies primarily selected, only eight met the criteria of inclusion. All studies performed intraoral examinations to diagnose oral lesions. According to results, the most frequent lesions were mucositis, candidiasis, periodontitis and gingivitis. The oral health condition from acute lymphocytic leukemia carriers varied according oral hygiene of the patient.
The results of studies identified such a great part of patients with ALL presented some lesion in oral cavity during or after chemotherapy treatment. The dentist surgeon needs to recognize oral manifestations and intervene in the oral health of patients with ALL, contributing and helping with treatment.
急性淋巴细胞白血病是一种最常见于儿童的癌症，其特征是骨髓中过度和紊乱的未成熟白细胞。
确定接受化疗治疗的急性淋巴细胞白血病患儿最常见的口腔表现。
本研究在电子数据库 PubMed/Medline、Science Direct、Scielo 和 Scopus 上进行。检索了全文呈递、以葡萄牙语、英语和西班牙语撰写、发表于 1992 年 1 月至 2013 年 4 月之间的论文。
从最初选择的研究中，只有八项符合纳入标准。所有研究均进行了口腔检查以诊断口腔病变。根据结果，最常见的病变是粘膜炎、念珠菌病、牙周炎和牙龈炎。急性淋巴细胞白血病患者的口腔健康状况因患者的口腔卫生状况而异。
研究结果表明，在化疗期间或之后，相当一部分 ALL 患者出现了口腔内的某些病变。牙医需要识别口腔表现并干预 ALL 患者的口腔健康，从而为治疗提供帮助。
