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神经功能受损早产儿斜视角度的长期变异性:一项12年随访研究

LONG-TERM VARIABILITY OF STRABISMUS ANGLE IN NEUROLOGICALLY IMPAIRED PREMATURE INFANTS: A 12-YEAR FOLLOW UP.

作者信息

Sardelić Ena, Utrobičić Dobrila Karlica

机构信息

1Pediatric Resident, Department of Pediatrics, Split University Hospital Centre, Split, Croatia; 2Department of Ophthalmology, Split University Hospital Centre, Split, Croatia.

出版信息

Acta Clin Croat. 2019 Sep;58(3):473-480. doi: 10.20471/acc.2019.58.03.11.

Abstract

The aim of this retrospective study was to determine the strabismus angle variability and rationality of surgical treatment of strabismus in prematurely born children with neurological impairment during 12-year follow up. Eleven premature infants born in 2003 were included in the study and treated with equal conservative approach from 2005 until 2016. Initial esotropia was found in seven and exotropia in four of eleven children. Changes in the strabismus angle correlated significantly with aging of the children. In children with initial esotropia, the strabismus angle became less convergent (less positive), changed the orientation and became more divergent with aging. In those with initial exotropia, the angle became less divergent (more positive), changed the orientation and became more convergent. Moreover, a significant difference in the strabismus angle was found during the 12-year follow up. Based on our results, due to the variability in strabismus angle, we did not find enough evidence for optimal timing or rationality of strabismus surgery in neurologically impaired children born prematurely.

摘要

这项回顾性研究的目的是确定神经功能受损的早产儿童在12年随访期间斜视角度的变异性以及斜视手术治疗的合理性。该研究纳入了2003年出生的11名早产婴儿,从2005年至2016年采用相同的保守方法进行治疗。11名儿童中,7名初始表现为内斜视,4名表现为外斜视。斜视角度的变化与儿童年龄显著相关。初始为内斜视的儿童,随着年龄增长,斜视角度的会聚程度减小(正值减小),方向改变,散开程度增加。初始为外斜视的儿童,随着年龄增长,斜视角度的散开程度减小(正值增大),方向改变,会聚程度增加。此外,在12年的随访期间发现斜视角度存在显著差异。基于我们的研究结果,由于斜视角度的变异性,我们没有找到足够的证据来证明神经功能受损的早产儿童进行斜视手术的最佳时机或合理性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff5f/6971793/bc245e7e80a3/acc-58-473-f1.jpg

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