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BEBIG钴高剂量率近距离放射治疗源在有限水模体中的径向剂量和各向异性函数的测量与蒙特卡罗计算。

Measurements and Monte Carlo calculation of radial dose and anisotropy functions of BEBIG Co high-dose-rate brachytherapy source in a bounded water phantom.

作者信息

Reddy Buchapudi Rekha, Chamberland Marc J P, Ravikumar Manickam, Varatharaj Chandraraj

机构信息

Department of Radiation Physics, Kidwai Memorial Institute of Oncology, Bangalore, India.

Carleton Laboratory for Radiotherapy Physics, Department of Physics, Carleton University, Ottawa, Canada.

出版信息

J Contemp Brachytherapy. 2019 Dec;11(6):563-572. doi: 10.5114/jcb.2019.91224. Epub 2019 Dec 25.

Abstract

PURPOSE

The study compared the experimentally measured radial dose function, g(), and anisotropy function, (,θ), of a BEBIG Co (Co0.A86) high-dose-rate (HDR) source in an in-house designed water phantom with egs_brachy Monte Carlo (MC) calculated values. MC results available in the literature were only for unbounded phantoms, and there are no currently published data in the literature for experimental data compared to MC calculations for a bounded phantom.

MATERIAL AND METHODS

egs_brachy is a fast EGSnrc application designed for brachytherapy applications. For unbounded phantom calculation, we considered a cylindrical phantom with a length and diameter of 80 cm and used liquid water. These egs_brachy calculated TG43U1 parameters were compared with the consensus data. Upon its validation, we experimentally measured g() and (,θ) in a precisely machined 30 × 30 × 30 cm water phantom using TLD-100 and EBT2 Gafchromic Film and compared it with the egs_brachy results of the same geometry.

RESULTS

The TG43U1 dosimetric dataset calculated using egs_brachy was compared with published data for an unbounded phantom, and found to be in good agreement within 2%. From our experimental results of g() and (,θ), the observed variation with the egs_brachy code calculation is found to be within the acceptable experimental uncertainties of 3%.

CONCLUSIONS

In this study, we validated the egs_brachy calculation of the TG43U1 dataset for the BEBIG Co source for an unbounded geometry. Subsequently, we measured the g() and (,θ) for the same source using an in-house water phantom. In addition, we validated these experimental results with the values calculated using the egs_brachy MC code, with the same geometry and similar phantom material as used in the experimental methods.

摘要

目的

本研究将内部设计的水模体中BEBIG钴(Co0.A86)高剂量率(HDR)源的实验测量径向剂量函数g()和各向异性函数(,θ)与egs_brachy蒙特卡罗(MC)计算值进行了比较。文献中可用的MC结果仅针对无界模体,目前尚无文献发表将有界模体的实验数据与MC计算结果进行比较的数据。

材料与方法

egs_brachy是一款专为近距离放射治疗应用设计的快速EGSnrc应用程序。对于无界模体计算,我们考虑了一个长度和直径均为80 cm的圆柱形模体,并使用液态水。将这些egs_brachy计算得到的TG43U1参数与共识数据进行了比较。验证后,我们使用TLD - 100和EBT2变色膜在精确加工的30×30×30 cm水模体中实验测量了g()和(,θ),并将其与相同几何形状的egs_brachy结果进行了比较。

结果

将使用egs_brachy计算得到的TG43U1剂量数据集与无界模体的已发表数据进行比较,发现二者在2%的范围内吻合良好。从我们对g()和(,θ)的实验结果来看,与egs_brachy代码计算结果的观测差异在3%的可接受实验不确定度范围内。

结论

在本研究中,我们验证了egs_brachy对无界几何形状的BEBIG钴源的TG43U1数据集的计算。随后,我们使用内部水模体测量了同一源的g()和(,θ)。此外,我们用egs_brachy MC代码计算的值验证了这些实验结果,计算时使用的几何形状和模体材料与实验方法中相同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eda5/6964345/412d91986f7f/JCB-11-39402-g001.jpg

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