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使用EGSnrc蒙特卡罗代码和EBT3 GAFChromic薄膜对近距离放射治疗计划系统进行调试验证

Commissioning Validation of a Brachytherapy Treatment Planning System with EGSnrc Monte Carlo Code and EBT3 GAFChromic Film.

作者信息

Lahlabou Mohammed, Khelifi Rachid

机构信息

Department of Radiotherapy, Central Hospital of the Army, Kouba, Algiers, Algeria.

PTHIRM Laboratory, Department of Physics, Faculty of Science, Saad Dahlab University Blida 1, Blida, Algeria.

出版信息

J Med Phys. 2022 Oct-Dec;47(4):352-361. doi: 10.4103/jmp.jmp_30_22. Epub 2023 Jan 10.

Abstract

AIMS

Most brachytherapy treatment planning system (TPS) commissioning requires data input based on the American Association of Physicists in Medicine Task Group-43 formalism. The commissioning accuracy is very important for dose calculation. The aim of this study is the implementation of a brachytherapy TPS into a clinical environment and check the TPS calculated dose accuracy.

SUBJECTS AND METHODS

After introducing data of the different catheters (CIS Bio International, Saclay, France), composed of several Cesium-137 Eckert and Ziegler BEBIG CSM-11 radioactive sources; for XiO (CMS, St. Louis) brachytherapy TPS, the TPS dose calculation accuracy was investigated by comparing between the TPS calculated dose distribution (DD) for all the catheters with (1) the measuring DD using EBT3 GAFChromic film and (2) calculating DD by egs_brachy (Electron Gamma Shower, National Research Council of Canada) Monte Carlo simulation. The phantom used for this study consists of six PTW slabs 30 cm × 30 cm × 1 cm of polymethyl methacrylate with a Delouche MEDpro applicator on the top. The TPS DD was calculated on the computed tomography scan of this phantom.

STATISTICAL ANALYSIS USED

PTW VeriSoft version 6.0.1.7 (PTW-Freiburg, Germany) software was used for analyzing scanned films and to perform the comparison based on the gamma index distribution.

RESULTS

For each catheter, the gamma index distribution showed agreement >95% of all pixels in both verification methods, with gamma ≤1.

CONCLUSIONS

We confirm the commissioning accuracy and that the TPS can be used for clinical purposes.

摘要

目的

大多数近距离放射治疗治疗计划系统(TPS)的调试需要基于美国医学物理学家协会任务组43形式主义输入数据。调试精度对于剂量计算非常重要。本研究的目的是将近距离放射治疗TPS应用于临床环境,并检查TPS计算剂量的准确性。

对象与方法

在输入由多个铯-137埃克特和齐格勒BEBIG CSM-11放射源组成的不同导管(法国萨克雷市CIS生物国际公司)的数据后;对于XiO(美国密苏里州圣路易斯市CMS公司)近距离放射治疗TPS,通过比较TPS计算的所有导管的剂量分布(DD)与(1)使用EBT3 GAFChromic胶片测量的DD以及(2)通过egs_brachy(加拿大国家研究委员会的电子伽马射线)蒙特卡罗模拟计算的DD,研究TPS剂量计算的准确性。本研究使用的模体由六个30 cm×30 cm×1 cm的聚甲基丙烯酸甲酯PTW板组成,顶部有一个Delouche MEDpro施源器。TPS DD是在该模体的计算机断层扫描上计算的。

所用统计分析方法

使用PTW VeriSoft 6.0.1.7版本(德国弗莱堡市PTW公司)软件分析扫描胶片,并基于伽马指数分布进行比较。

结果

对于每个导管,在两种验证方法中,伽马指数分布显示所有像素的一致性>95%,伽马≤1。

结论

我们证实了调试的准确性,并且该TPS可用于临床目的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec0d/9997537/54466197c6a1/JMP-47-352-g001.jpg

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