Park Chan-Hong, Chun Sungwook
Health Care Division, The Provincial Office of Jeollanamdo, Muan, Korea.
Department of Obstetrics and Gynecology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.
Obstet Gynecol Sci. 2020 Jan;63(1):80-86. doi: 10.5468/ogs.2020.63.1.80. Epub 2019 Dec 20.
This study aimed to assess the effect of combined oral contraceptives (COCs) on polycystic ovarian morphology (PCOM) and serum anti-Müllerian hormone (AMH) levels in Korean women with polycystic ovary syndrome (PCOS).
This university hospital study enrolled 36 Korean women who were newly diagnosed with PCOS based on the Rotterdam criteria and were treated with COCs for at least 1 year. We retrospectively evaluated the ovarian volume and number of antral follicles using ultrasonography and assessed serum AMH levels at baseline and after 1 year of COC treatment.
Significant decreases in ovarian volume and antral follicle count were observed after 1 year of COC treatment. Compared to baseline, serum AMH levels were significantly decreased after 1 year.
COC treatment significantly affects ultrasound-assessed PCOM and serum AMH levels of patients with PCOS.
本研究旨在评估复方口服避孕药(COC)对患有多囊卵巢综合征(PCOS)的韩国女性的多囊卵巢形态(PCOM)和血清抗苗勒管激素(AMH)水平的影响。
这项大学医院研究纳入了36名根据鹿特丹标准新诊断为PCOS且接受COC治疗至少1年的韩国女性。我们使用超声回顾性评估卵巢体积和窦卵泡数量,并在基线时和COC治疗1年后评估血清AMH水平。
COC治疗1年后观察到卵巢体积和窦卵泡计数显著下降。与基线相比,1年后血清AMH水平显著降低。
COC治疗对PCOS患者经超声评估的PCOM和血清AMH水平有显著影响。