Keshavan M S, Moodley P, Eales M, Joyce E, Yeragani V K
Western Psychiatric Institute and Clinic, Pittsburgh, Pa.
Can J Psychiatry. 1988 Oct;33(7):626-7. doi: 10.1177/070674378803300709.
Withdrawal from long-term treatment with benzodiazepines was followed in three patients by a severe delusional depression. The delusional depression may be related to the neurotransmitter changes accompanying benzodiazepine withdrawal. Caution should be exercised in long-term use of benzodiazepines in susceptible individuals.
三名长期使用苯二氮䓬类药物治疗的患者在停药后出现了严重的妄想性抑郁症。妄想性抑郁症可能与苯二氮䓬类药物戒断伴随的神经递质变化有关。对于易感个体,长期使用苯二氮䓬类药物时应谨慎。