The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109th Xueyuanxi Road, Wenzhou, Zhejiang Province, China.
Support Care Cancer. 2020 Oct;28(10):4721-4727. doi: 10.1007/s00520-019-05289-9. Epub 2020 Jan 22.
In this study, Problem Management Plus (PM+) was used for patients with multiple myeloma (MM), to develop a care model of psychology and quality of life.
Forty cases received psychological management (PM+ group), and 40 cases underwent investigation without management (non-PM+ group). Patients were assessed using PSYCHLOPS, WHO DAS 2.0, and HADS (see Supplementary File 1).
The results showed that the PM+ group showed reductions in Psychological Outcome Profile scores (6.3 ± 2.9) following program completion (preprogram scores: 16.0 ± 1.9, P < .05). The non-PM+ group showed differences between preprogram (16.7 ± 1.8) and postprogram scores (14.8 ± 2.6, P < .05). The effect size of the PM+ group exceeded that of the non-PM+ group (5.1 to 1.0). In the Hospital Anxiety and Depression Scale, the PM+ group showed reductions in anxiety (6.4 ± 1.8) and depression (5.4 ± 0.7) (preprogram scores: 14.7 ± 4.3, P < .05 and 10.9 ± 2.6, P < .05, respectively). In the Hospital Anxiety and Depression Scale, scores for mobility, self-care, getting along, life activities, and participation decreased in the PM+ group following program completion (all P's < .05) but did not decrease in the non-PM+ group (all P > .05).
The PM+ strategy could help patients to alleviate symptoms of anxiety and depression and strengthen social support, to aid in the management of problems and improve mental disorders.
MM patients often experienced mental disorders and wished to participate in psychosocial interventions; the PM+ strategies should be as a wide to help patients manage their problems and alleviate the symptoms of anxiety and depression.
本研究采用问题管理 Plus（PM+）对多发性骨髓瘤（MM）患者进行心理和生活质量的护理模式。
40 例患者接受心理管理（PM+组），40 例患者未进行管理（非 PM+组）。采用 PSYCHLOPS、WHO DAS 2.0 和 HADS 评估患者（见补充文件 1）。
结果显示，方案完成后 PM+组心理结局评分降低（6.3±2.9）（方案前评分：16.0±1.9，P<.05）。非 PM+组方案前后评分存在差异（16.7±1.8 和 14.8±2.6，P<.05）。PM+组的效果大小大于非 PM+组（5.1 到 1.0）。在医院焦虑抑郁量表中，PM+组焦虑（6.4±1.8）和抑郁（5.4±0.7）评分降低（方案前评分：14.7±4.3，P<.05 和 10.9±2.6，P<.05）。在医院焦虑抑郁量表中，PM+组方案完成后活动、自理、交往、生活活动和参与维度评分下降（均 P<.05），而非 PM+组无下降（均 P>.05）。
PM+策略可帮助患者缓解焦虑抑郁症状，增强社会支持，辅助处理问题，改善精神障碍。
MM 患者常有精神障碍，希望参与心理社会干预；PM+策略应广泛应用，帮助患者管理问题，缓解焦虑和抑郁症状。
