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口腔扁平苔藓患者与对照组的心理障碍和生活质量。

Psychological disorders and quality of life in oral lichen planus patients and a control group.

机构信息

Oral Medicine, Oral Surgery and Implantology Unit, Faculty of Medicine and Dentistry, Santiago de Compostela, Spain.

Oral Medicine, Oral Surgery and Implantology Unit, Faculty of Medicine and Dentistry, Instituto de Investigación Sanitaria de Santiago (IDIS), Santiago de Compostela, Spain.

出版信息

Oral Dis. 2019 Sep;25(6):1645-1651. doi: 10.1111/odi.13106. Epub 2019 May 29.

Abstract

OBJECTIVES

Oral lichen planus (OLP) is a common disease whose aetiopathogenesis is linked to psychological disorders. This study aims to determine the influence of anxiety and depression in OLP patients, define the perception of quality of life in these patients and check for potential differences between atrophic/ ulcerative and reticular lesions.

MATERIALS AND METHODS

A group of 48 OLP patients and a control group of 40 patients were selected. In order to assess anxiety, depression and quality of life, Hospital Anxiety and Depression Scale (HADS) and Oral Health Impact Profile 14 (OHIP-14) tests were completed.

RESULTS

OLP patients showed higher scores on HADS (anxiety p < 0.01, depression p < 0.05) and OHIP-14 (physical pain p < 0.05, psychological discomfort p = 0.001). Patients with reticular lesions obtained higher scores in HADS (anxiety p = 0.001, depression p < 0.001), whereas patients with atrophic/ ulcerative lesions obtained higher scores in OHIP-14 (p = 0.02).

CONCLUSIONS

Psychological disorders play an important role as a trigger for OLP and are responsible for many relapses. Psychological support would be advisable in order to improve their mental health, as this would have a positive impact on their quality of life and would lead to a better progression of the disease.

摘要

目的

口腔扁平苔藓(OLP)是一种常见疾病,其发病机制与心理障碍有关。本研究旨在确定焦虑和抑郁对 OLP 患者的影响,定义这些患者的生活质量感知,并检查萎缩/溃疡性和网状病变之间的潜在差异。

材料和方法

选择了一组 48 名 OLP 患者和一组 40 名对照组患者。为了评估焦虑、抑郁和生活质量,完成了医院焦虑和抑郁量表(HADS)和口腔健康影响概况 14 项(OHIP-14)测试。

结果

OLP 患者在 HADS(焦虑 p<0.01,抑郁 p<0.05)和 OHIP-14(躯体疼痛 p<0.05,心理不适 p=0.001)方面的得分更高。网状病变患者在 HADS(焦虑 p=0.001,抑郁 p<0.001)方面的得分更高,而萎缩/溃疡性病变患者在 OHIP-14(p=0.02)方面的得分更高。

结论

心理障碍作为 OLP 的触发因素起着重要作用,并导致许多复发。为了改善他们的心理健康,提供心理支持是明智的,因为这将对他们的生活质量产生积极影响,并导致疾病更好地进展。

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