Boucher C A, de Gans J, van Oers R, Danner S, Goudsmit J
Human Retrovirus Laboratory, Academic Medical Center, Amsterdam, The Netherlands.
Clin Neurol Neurosurg. 1988;90(3):235-6. doi: 10.1016/0303-8467(88)90027-3.
A 58-year-old patient suffering from Guillain-Barré syndrome was successfully treated with plasma exchange therapy. Two- and half year later she developed AIDS. The only risk factor of this patient was plasmapheresis and it appeared, retrospectively, that one of the plasma donor samples contained antibodies to HIV. Knowing the exact moment of infection of our patient we documented the transfer of HIV antibodies from donor to patient, a HIV antigen peak two weeks after transmission (reflecting the initial virus replication in the patient) and subsequently the occurrence of patients' HIV antibodies and the reoccurrence of HIV antigen at the moment AIDS was diagnosed.
一名58岁患有吉兰-巴雷综合征的患者通过血浆置换疗法成功治愈。两年半后她患上了艾滋病。该患者唯一的风险因素是血浆置换，回顾发现，其中一份血浆供体样本含有抗HIV抗体。由于我们知道患者的确切感染时间，因此记录了HIV抗体从供体转移到患者体内的过程，在病毒传播两周后出现了HIV抗原峰值（反映了患者体内最初的病毒复制情况），随后在诊断出艾滋病时患者出现了HIV抗体以及HIV抗原再次出现的情况。
