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神经系统疾病患者血浆置换的并发症。

Complications of plasma exchange in patients with neurological diseases.

作者信息

Henze T, Prange H W, Talartschik J, Rumpf K W

机构信息

Abteilung für Neurologie, Georg-August-Universität, Göttingen.

出版信息

Klin Wochenschr. 1990 Dec 4;68(23):1183-8. doi: 10.1007/BF01815277.

Abstract

Plasma exchange has proven to be effective in diseases of established or presumed autoimmune etiology as well as in hyperviscosity syndromes and some rare metabolic disorders. Its application is thought to be relatively safe; nevertheless, severe complications may occur. We therefore analyzed the complications of 291 exchanges in 39 patients with neurological diseases. Minor complications developed in 4.8% and major complications in 2.7% of procedures, including one death. Severe infections and technical problems have been the most serious side effects, sometimes followed by organ failure or even death.

摘要

血浆置换已被证明对已确诊或疑似自身免疫性病因的疾病、高粘滞综合征及某些罕见代谢紊乱有效。其应用被认为相对安全;然而,仍可能发生严重并发症。因此,我们分析了39例神经系统疾病患者291次血浆置换的并发症。在4.8%的操作中出现轻微并发症,2.7%出现严重并发症,包括1例死亡。严重感染和技术问题一直是最严重的副作用,有时还会继发器官衰竭甚至死亡。

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本文引用的文献

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Complications of plasma exchange in neurological patients.神经系统疾病患者血浆置换的并发症
Arch Neurol. 1982 Jun;39(6):350-4. doi: 10.1001/archneur.1982.00510180028007.
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The complications of therapeutic plasma exchange.治疗性血浆置换的并发症。
Vox Sang. 1984;46(5):270-6. doi: 10.1111/j.1423-0410.1984.tb00086.x.
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Therapeutic plasma exchange.治疗性血浆置换
N Engl J Med. 1984 Mar 22;310(12):762-71. doi: 10.1056/NEJM198403223101206.
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Complications of plasma exchange.血浆置换的并发症。
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