草药混合物（TJ - 960，SK）对E1小鼠戊四氮诱导惊厥的抑制作用。
Inhibitory effect of a mixture of herbal drugs (TJ-960, SK) on pentylenetetrazol-induced convulsions in E1 mice.
作者信息
Sugaya E, Ishige A, Sekiguchi K, Iizuka S, Sugimoto A, Yuzurihara M, Hosoya E
机构信息
Department of Physiology, Kanagawa Dental College, Yokosuka, Japan.
出版信息
Epilepsy Res. 1988 Sep-Oct;2(5):337-9. doi: 10.1016/0920-1211(88)90043-5.
PMID:3197702
Abstract
TJ-960 is a spray-dried mixture of 9 herbal drugs. The convulsions of E1 mice induced by pentylenetetrazol (18 mg/kg) were completely inhibited by p.o. administration of TJ-960 at a daily dose of 1.0 g/kg both in 8-week-old and 4-week-old E1 mice. These findings suggest that TJ-960 has an inhibitory effect on the convulsions of this hereditary animal model of epilepsy.
摘要
TJ - 960是9种草药的喷雾干燥混合物。戊四氮（18毫克/千克）诱导的E1小鼠惊厥，在8周龄和4周龄的E1小鼠中，口服每日剂量为1.0克/千克的TJ - 960均可完全抑制。这些发现表明TJ - 960对这种遗传性癫痫动物模型的惊厥具有抑制作用。
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