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淋巴细胞性胃炎:一种新描述的疾病:一项回顾性内镜及组织学研究。

Lymphocytic gastritis: a newly described entity: a retrospective endoscopic and histological study.

作者信息

Haot J, Hamichi L, Wallez L, Mainguet P

机构信息

Department of Pathological Anatomy, Université Catholique de Louvain, Brussels, Belgium.

出版信息

Gut. 1988 Sep;29(9):1258-64. doi: 10.1136/gut.29.9.1258.

DOI:10.1136/gut.29.9.1258
PMID:3198002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1434343/
Abstract

Lymphocytic gastritis is a histopathological entity characterised by the accumulation of small lymphocytes in the surface and foveolar epithelium. In order to investigate the correlation between endoscopy and histology in this condition, 192 observations selected on the basis of a presumed diagnosis of erosive or varioliform gastritis were reviewed. Ninety two instances corresponded to lymphocytic gastritis, while 100 did not show any particular microscopic feature and were labelled non-specific gastritis. There was a good correlation (48 of 58) between the diagnosis of the so-called varioliform gastritis and the histological evidence of lymphocytic gastritis. The correlation was even better when nodules, erosions, and enlarged folds were considered. Lymphocytic gastritis has a typical endoscopical appearance consisting of nodules, erosions, and large folds predominating in the gastric body. This contrasts with non-specific gastritis, which affects the antrum and produces erosions on a flat mucosa.

摘要

淋巴细胞性胃炎是一种组织病理学实体,其特征是在表面和小凹上皮中积聚小淋巴细胞。为了研究这种情况下内镜检查与组织学之间的相关性,我们回顾了192例基于糜烂性或痘疮样胃炎的假定诊断而选择的观察病例。92例符合淋巴细胞性胃炎,而100例未显示任何特殊的微观特征,被标记为非特异性胃炎。所谓痘疮样胃炎的诊断与淋巴细胞性胃炎的组织学证据之间存在良好的相关性(58例中有48例)。当考虑结节、糜烂和皱襞增大时,相关性更好。淋巴细胞性胃炎具有典型的内镜表现,包括结节、糜烂和以胃体为主的大皱襞。这与非特异性胃炎形成对比,非特异性胃炎累及胃窦并在平坦的黏膜上产生糜烂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/1434343/06587132eee8/gut00235-0128-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/1434343/ddb5eafa6971/gut00235-0125-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/1434343/6f697339329b/gut00235-0125-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/1434343/216d76515b60/gut00235-0127-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/1434343/6efc5765307f/gut00235-0127-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/1434343/8f6ecb3d989c/gut00235-0127-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/1434343/06587132eee8/gut00235-0128-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/1434343/ddb5eafa6971/gut00235-0125-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/1434343/6f697339329b/gut00235-0125-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/1434343/216d76515b60/gut00235-0127-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/1434343/6efc5765307f/gut00235-0127-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/1434343/8f6ecb3d989c/gut00235-0127-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/1434343/06587132eee8/gut00235-0128-a.jpg

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本文引用的文献

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Primary gastric lymphoma--a tumour of mucosa-associated lymphoid tissue. A histological and immunohistochemical study of 36 cases.原发性胃淋巴瘤——一种黏膜相关淋巴组织肿瘤。36例病例的组织学和免疫组织化学研究
胃炎:病因特征和组织学实用方法的最新进展。
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The coeliac stomach: gastritis in patients with coeliac disease.乳糜泻患者的胃部:乳糜泻患者的胃炎
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Helicobacter pylori Associated Lymphocytic Gastritis in a Child.一名儿童的幽门螺杆菌相关性淋巴细胞性胃炎
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Upregulation of cathepsin W-expressing T cells is specific for autoimmune atrophic gastritis compared to other types of chronic gastritis.与其他类型的慢性胃炎相比,表达组织蛋白酶W的T细胞上调是自身免疫性萎缩性胃炎所特有的。
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