阿普斯特成功治疗难治性掌跖脓疱病。
Refractory palmoplantar pustulosis succesfully treated with apremilast.
作者信息
Carrascosa de Lome Raquel, Conde Montero Elena, de la Cueva Dobao Pablo
机构信息
Dermatology Department, Hospital Universitario Infanta Leonor, Madrid, Spain.
出版信息
Dermatol Ther. 2020 Mar;33(2):e13230. doi: 10.1111/dth.13230. Epub 2020 Feb 9.
Palmoplantar pustulosis is a chronic inflammatory disease which characterized by a eruption of sterile pustules on the palms and soles. Apremilast is an oral phosphodiesterase-4 inhibitor which is approved for the treatment of chronic plaque psoriasis and psoriatic arthritis. However, no clinical trial has been performed to confirm the efficacy of apremilast for palmoplantar pustulosis yet. Moreover, there are very few cases of this disease treated with apremilast. Herein, we describe a case of a refractory palmoplantar pustulosis succesfully treated with apremilast.
掌跖脓疱病是一种慢性炎症性疾病，其特征为手掌和脚底出现无菌性脓疱。阿普米司特是一种口服磷酸二酯酶-4抑制剂，已被批准用于治疗慢性斑块型银屑病和银屑病关节炎。然而，尚未进行临床试验来证实阿普米司特治疗掌跖脓疱病的疗效。此外，用阿普米司特治疗这种疾病的病例非常少。在此，我们描述一例用阿普米司特成功治疗的难治性掌跖脓疱病病例。
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