Perth Children's Hospital, Perth, WA.
University of Western Australia, Perth, WA.
Med J Aust. 2020 Apr;212(6):271-275. doi: 10.5694/mja2.50484. Epub 2020 Jan 25.
To estimate the proportion of infants introduced to peanut and other common food allergens by 12 months of age; to collect information about parent-reported reactions to food.
DESIGN, SETTING: Observational cohort study, applying the SmartStartAllergy SMS protocol and online questionnaire to parents of 12-month-old infants attending 69 Australian general practices between 21 September 2018 and 3 May 2019.
3374 parents recruited via the 69 participating general practices.
Proportions of infants who had eaten peanut and other common food allergens; proportions with parent-reported reactions to food.
1940 of 3374 invited parents participated in the study (response rate, 57%), of whom 836 (46%) completed the online questionnaire. At 12 months of age, 1673 of 1940 infants had eaten peanut-including foods (86.2%; 95% confidence interval [CI], 84.6-87.7%); 235 of 1831 parents (12.8%; 95% CI, 11.3-14.5%) reported food-related reactions. Questionnaire responses indicated that dairy was the food type most frequently reported to cause a food-related reaction (72 of 835 exposed infants, 8.6%; 95% CI, 6.8-11%); peanut-related reactions were reported for 20 of 764 exposed children (2.6%; 95% CI, 1.6-4.0%). 97 of 250 parent-reported reactions to food (39%) did not include symptoms that suggested an IgE-mediated allergic reaction.
Infant feeding practices in Australia have changed over the past decade; a large majority of infants are now fed peanut before 12 months of age. The SmartStartAllergy program allows monitoring of infant feeding practices in primary care, as well as of parent-reported reactions to food in infants.
估计 12 个月龄婴儿引入花生和其他常见食物过敏原的比例；收集有关父母报告的食物过敏反应信息。
设计、地点：观察性队列研究，应用 SmartStartAllergy SMS 方案和在线问卷，对 2018 年 9 月 21 日至 2019 年 5 月 3 日期间参加澳大利亚 69 家普通诊所的 12 个月龄婴儿的父母进行调查。
通过 69 家参与的普通诊所招募的 3374 名父母。
食用花生和其他常见食物过敏原的婴儿比例；父母报告的食物过敏反应比例。
3374 名受邀父母中有 1940 名（37.4%）参加了研究（应答率为 57%），其中 836 名（46%）完成了在线问卷。在 12 个月龄时，1940 名婴儿中有 1673 名（86.2%；95%置信区间[CI]，84.6-87.7%）食用过含花生的食物；1831 名父母中有 235 名（12.8%；95% CI，11.3-14.5%）报告了与食物相关的反应。问卷回答表明，引起与食物相关的反应最常见的食物类型是乳制品（72/835 名暴露婴儿，8.6%；95% CI，6.8-11%）；764 名暴露儿童中有 20 名（2.6%；95% CI，1.6-4.0%）报告了与花生相关的反应。250 名父母报告的与食物相关的反应中有 97 例（39%）不包括提示 IgE 介导的过敏反应的症状。
在过去十年中，澳大利亚婴儿喂养方式发生了变化；现在绝大多数婴儿在 12 个月龄之前食用花生。SmartStartAllergy 计划允许在初级保健中监测婴儿喂养方式，以及婴儿父母报告的食物过敏反应。
