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超声检查在雌性猩猩妇产科诊断中的应用及尿中性激素的测量

Gynaecological diagnosis by ultrasound and the measurement of urinary sex steroid hormones in female orangutans.

机构信息

Wildlife Research Center, Kyoto University, Kyoto, Japan.

Chiba Zoological Park, Chiba, Japan.

出版信息

Vet Med Sci. 2020 Aug;6(3):612-616. doi: 10.1002/vms3.237. Epub 2020 Jan 25.

DOI:10.1002/vms3.237
PMID:31981464
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7397886/
Abstract

Gynaecological diagnoses were carried in three adult female orangutans (Pongo spp.) using ultrasound, and their estrous states were estimated by measuring urinary sex steroid hormone concentrations using enzyme immunoassay. Ultrasound diagnosis revealed that the endometrial thickness and follicle size were correlated with the oestrogen-3-glucuronide concentrations in the follicular phase. In addition, administration of the ovulation inducer human chorionic gonadotropin (hCG) had the strongest effect on the pregnanediol-3-glucuronide (PdG) concentration when the follicle size was 22.3 mm, suggesting that the follicle reaches this size before ovulation. The similarity between this and the maximum ovarian follicle size in humans (approximately 20 mm) indicates that the ancestral reproductive characteristics may have been retained in these species.

摘要

对 3 只成年雌性猩猩(Pongo spp.)进行了妇科诊断,使用了超声技术,并通过酶免疫分析法测量尿液中的性激素浓度来估计其发情状态。超声诊断表明,在卵泡期,子宫内膜厚度和卵泡大小与雌三醇-3-葡萄糖醛酸苷浓度相关。此外,当卵泡大小为 22.3 毫米时,排卵诱导剂人绒毛膜促性腺激素(hCG)的给药对孕二醇-3-葡萄糖醛酸苷(PdG)浓度的影响最强,这表明卵泡在排卵前达到这个大小。这与人类最大卵巢卵泡大小(约 20 毫米)相似,表明这些物种可能保留了祖先的生殖特征。

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