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在使用主动脉根部再植入技术修复二叶式主动脉瓣病变时,有两种不同的主动脉新根部的几何取向。

Two different geometric orientations for aortic neoroot creation in bicuspid aortic valve repair with root reimplantation.

机构信息

Division of Cardiovascular Surgery, University of Pennsylvania, Philadelphia, Pa.

Division of Cardiovascular Surgery, University of Pennsylvania, Philadelphia, Pa.

出版信息

J Thorac Cardiovasc Surg. 2020 Jul;160(1):47-57. doi: 10.1016/j.jtcvs.2019.06.119. Epub 2019 Aug 30.

Abstract

OBJECTIVE

Bicuspid aortic valve (BAV) represents 2 cusps oriented along a spectrum of equal (180°/180°) or unequal (150°/210°) leaflet surface area distribution along the aortic annular plane. We have taken the approach of respecting the native geometric orientation of the repaired BAV leaflets when creating the aortic neoroot during valve-sparing root reimplantation (VSRR) procedures. We investigated midterm outcomes with this 2-prong approach for VSRR in BAV syndrome.

METHODS

Of 72 patients in a prospectively maintained BAV repair database, 68 met inclusion criteria: 36 patients had 180°/180° neoroot geometry, and 32 patients had 150°/210° orientation. A multivariate ordinal logistic mixed effects model was performed to study parameters associated with recurrent AI greater than 2+.

RESULTS

Preoperative parameters were similar between 180°/180° and 150°/210° groups, except for greater incidence of AI 4+ in the latter (50.0% [n = 16] vs 8.3% [n = 3]; P < .001). Postoperatively, stroke, renal failure, reoperation for bleeding, and pacemaker rates were 0 in the entire cohort. In-hospital/30-day mortality in the entire cohort was 1.5% (n = 1). Multivariate ordinal logistic mixed effects model showed that preoperative AI greater than 3+ (odds ratio, 0.4; P = .46) and geometric orientation of the aortic neoroot (odds ratio, 3.8; P = .25) were not significantly associated with recurrence of AI greater than 2+.

CONCLUSIONS

Respecting BAV geometry for VSRR neoroot creation yields excellent midterm outcomes and may minimize conjoint cusp leaflet stress that may occur in "forcing" a 150°/210° type I BAV into a 180°/180° neoroot.

摘要

目的

二叶式主动脉瓣(BAV)代表 2 个沿着主动脉瓣环平面的瓣叶面积分布在等(180°/180°)或不等(150°/210°)范围内的瓣叶。在进行保留瓣膜的主动脉根部再植入(VSRR)手术时,我们采用了尊重修复后的 BAV 瓣叶固有几何取向的方法来构建主动脉新根部。我们研究了这种用于 BAV 综合征的 VSRR 的双管齐下方法的中期结果。

方法

在一个前瞻性维护的 BAV 修复数据库中,共有 72 名患者符合纳入标准:36 名患者具有 180°/180°的新根部几何形状,32 名患者具有 150°/210°的取向。采用多变量有序逻辑混合效应模型来研究与大于 2+的复发性 AI 相关的参数。

结果

180°/180°和 150°/210°组的术前参数相似,但后者 AI 4+的发生率更高(50.0%[n=16]与 8.3%[n=3];P<.001)。术后,整个队列中没有发生中风、肾衰竭、再次出血手术和起搏器的情况。整个队列的住院/30 天死亡率为 1.5%(n=1)。多变量有序逻辑混合效应模型显示,术前 AI 大于 3+(优势比,0.4;P=0.46)和主动脉新根部的几何形状(优势比,3.8;P=0.25)与 AI 大于 2+的复发无显著相关性。

结论

在 VSRR 新根部的创建中尊重 BAV 几何形状可获得出色的中期结果,并可能最小化可能在“强制”将 150°/210°I 型 BAV 放入 180°/180°新根部时发生的联合瓣叶应力。

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