Shandong First Medical University & Shandong Academy of Medical Sciences, Shandong Provincial Qianfoshan Hospital, No 16766 Jingshi Road, Lixia District, Jinan, Shandong 250014, PR China.
The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, No 16766 Jingshi Road, Lixia District, Jinan, Shandong 250014, PR China.
Am J Otolaryngol. 2020 May-Jun;41(3):102403. doi: 10.1016/j.amjoto.2020.102403. Epub 2020 Jan 17.
Laryngopharyngeal reflux (LPR) accounts for 4-10% of outpatient visits. The standard domestic LPR diagnostic tools are the reflux finding score (RFS) and reflux symptom index (RSI). Narrow band imaging (NBI) can identify previously unknown characteristic microvessel features. Our aim was to explore the role of NBI in LPR diagnosis.
We recruited 56 LPR outpatients and 41 symptom-negative controls. All individuals received RSI and RFS scores and underwent 24-hour multichannel intraluminal impedance-PH (MII-pH) monitoring and endoscopic NBI before and after treatment. The positivity rates in the study and control groups, before and after treatment, and using NBI and the conventional method were evaluated.
Fifty-one LPR and six control patients had sparse light brownish dots or tufted light brownish dots in the postcricoid region. The RSI and RFS positivity rates were 31.3% and 87.1%, respectively. NBI is as effective as the RFS (P < 0.05), and has poor consistency with the RSI (P < 0.05). Fifty-three LPR patients underwent posttreatment laryngoscopy. The positivity rate decreased to 17.0% (P < 0.05).
NBI has good value for LPR diagnosis.
喉咽反流(LPR)占门诊就诊的 4-10%。国内 LPR 的标准诊断工具是反流症状评分(RFS)和反流症状指数(RSI)。窄带成像(NBI)可以识别以前未知的特征微血管特征。我们的目的是探讨 NBI 在 LPR 诊断中的作用。
我们招募了 56 名 LPR 门诊患者和 41 名无症状对照者。所有患者均接受 RSI 和 RFS 评分,并在治疗前后进行 24 小时多通道腔内阻抗-PH(MII-pH)监测和内镜 NBI。评估研究组和对照组、治疗前后、使用 NBI 和常规方法的阳性率。
51 例 LPR 患者和 6 例对照组患者在环后区有稀疏的浅棕色斑点或簇状浅棕色斑点。RSI 和 RFS 的阳性率分别为 31.3%和 87.1%。NBI 与 RFS 一样有效(P<0.05),与 RSI 一致性差(P<0.05)。53 例 LPR 患者接受了治疗后喉镜检查。阳性率下降至 17.0%(P<0.05)。
NBI 对 LPR 诊断具有良好的价值。