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极地探险:蛋白质极性定位的机制。

Polar expedition: mechanisms for protein polar localization.

机构信息

Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences (SLU), 90183 Umeå, Sweden.

Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences (SLU), 90183 Umeå, Sweden.

出版信息

Curr Opin Plant Biol. 2020 Feb;53:134-140. doi: 10.1016/j.pbi.2019.12.001. Epub 2020 Jan 23.

Abstract

Most cells show asymmetry in their shape or in the organization of their components that results in poles with different properties. This is a fundamental feature that participates in modulating the development of an organism and its responses to external stimuli. In plants, a number of proteins that are important for developmental and physiological processes have been shown to display polar localization. However, how these polarities are established, maintained, or dynamically modulated is still largely unclear for most of these proteins. In this review we report recent updates on the mechanisms of polar protein localization, focusing on a subset of these proteins that are the focus of current research efforts.

摘要

大多数细胞在形状或组成成分的组织上表现出不对称性,从而形成具有不同性质的两极。这是一个基本特征,参与调节生物体的发育及其对外界刺激的反应。在植物中,已经证明许多对发育和生理过程很重要的蛋白质具有极性定位。然而,对于这些蛋白质中的大多数,这些极性是如何建立、维持或动态调节的仍然在很大程度上不清楚。在这篇综述中,我们报告了极性蛋白定位机制的最新进展,重点介绍了当前研究工作的重点的这些蛋白质中的一部分。

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