Suppr超能文献

拉姆齐亨特综合征:特征和患者自我评估的长期面瘫结局。

Ramsay Hunt syndrome: characteristics and patient self-assessed long-term facial palsy outcome.

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Helsinki University Hospital and University of Helsinki, PO Box 263, 00029 HUS, Helsinki, Finland.

Terveystalo Occupational Healthcare Services, Leppavaara and Espoontori, Espoo, Finland.

出版信息

Eur Arch Otorhinolaryngol. 2020 Apr;277(4):1235-1245. doi: 10.1007/s00405-020-05817-y. Epub 2020 Jan 25.

Abstract

PURPOSE

To explore the characteristics, medical treatments, and long-term facial palsy outcome in Ramsay Hunt syndrome.

METHODS

Patient questionnaire including self-assessment of long-term facial palsy outcome and retrospective chart review. Initial facial palsy grade was compared to self-assessed or patient record stated palsy outcome. Occurrence of different characteristics (blisters, hearing loss, vertigo, etc.) of the syndrome were assessed.

RESULTS

Altogether 120 patients were included of which 81 answered the questionnaire. All but one patient had received virus medication (aciclovir, valaciclovir), and half received simultaneous corticosteroids. If the medication was started within 72 h of Ramsay Hunt diagnosis, facial palsy recovered totally or with only slight sequelae in over 80% of the patients. Only a minority of the patients experienced varicella blisters simultaneously with facial palsy, blisters more often preceded or followed the palsy. Approximately 20% of the patients had their blisters in hidden places in the ear canal or mouth.

CONCLUSIONS

The long-term outcome of facial palsy in medically treated Ramsay Hunt syndrome was approaching the outcome of Bell's palsy. It is crucial to ask and inform the patient about the blisters and look for them since, more often than not, the blisters precede or follow the palsy and can be in areas not easily seen.

摘要

目的

探讨 Ramsay Hunt 综合征的特点、治疗方法及长期面瘫结局。

方法

采用患者问卷调查,包括面瘫长期结局的自我评估和回顾性病历审查。比较初始面瘫分级与自我评估或患者记录的面瘫结局。评估综合征的不同特征(水疱、听力损失、眩晕等)的发生情况。

结果

共纳入 120 例患者,其中 81 例回答了问卷。除 1 例患者外,所有患者均接受了病毒药物(阿昔洛韦、伐昔洛韦)治疗,半数患者同时接受了皮质类固醇治疗。如果在 Ramsay Hunt 综合征诊断后 72 小时内开始用药,超过 80%的患者面瘫完全或仅有轻微后遗症恢复。仅有少数患者同时出现水痘样水疱和面瘫,水疱更常见于面瘫之前或之后。约 20%的患者耳内或口腔的水疱位于隐蔽部位。

结论

经药物治疗的 Ramsay Hunt 综合征的面瘫长期结局接近贝尔面瘫。询问并告知患者有关水疱的情况并寻找水疱非常重要,因为水疱通常先于或后于面瘫出现,而且可能位于不易看到的部位。

相似文献

3
Comparative prognosis in patients with Ramsay-Hunt syndrome and Bell's palsy.拉姆齐-亨特综合征与贝尔麻痹患者的预后比较
Eur Arch Otorhinolaryngol. 2019 Apr;276(4):1011-1016. doi: 10.1007/s00405-019-05300-3. Epub 2019 Feb 1.
4
Ramsay Hunt syndrome.拉姆齐·亨特综合征
J Neurol Neurosurg Psychiatry. 2001 Aug;71(2):149-54. doi: 10.1136/jnnp.71.2.149.
9
[Clinical and therapeutic features of herpes zoster oticus: a case report].[耳带状疱疹的临床与治疗特征:一例报告]
Pan Afr Med J. 2022 Mar 3;41:171. doi: 10.11604/pamj.2022.41.171.33711. eCollection 2022.
10
[Facial palsy].[面神经麻痹]
Rev Med Brux. 2013 Sep;34(4):221-5.

引用本文的文献

3
Vestibulopathy in Patients Presenting With Ramsay Hunt Syndrome.伴有拉姆齐·亨特综合征患者的前庭病变
Otol Neurotol Open. 2024 Dec 13;4(4):e064. doi: 10.1097/ONO.0000000000000064. eCollection 2024 Dec.

本文引用的文献

2
Clinical manifestations in patients with herpes zoster oticus.耳带状疱疹患者的临床表现。
Eur Arch Otorhinolaryngol. 2016 Jul;273(7):1739-43. doi: 10.1007/s00405-015-3756-9. Epub 2015 Aug 26.
4
Ramsay Hunt syndrome.拉姆齐·亨特综合征。
Eur Ann Otorhinolaryngol Head Neck Dis. 2012 Feb;129(1):22-5. doi: 10.1016/j.anorl.2011.08.003. Epub 2012 Feb 24.
7
Sunnybrook and House-Brackmann systems in 5397 facial gradings.5397 例面部分级的 Sunnybrook 和 House-Brackmann 系统。
Otolaryngol Head Neck Surg. 2011 Apr;144(4):570-4. doi: 10.1177/0194599810397497. Epub 2011 Feb 24.
8
Ramsay Hunt syndrome with multicranial nerve involvement.伴有多组颅神经受累的拉姆齐·亨特综合征
Acta Otolaryngol. 2011 Feb;131(2):210-5. doi: 10.3109/00016489.2010.520167. Epub 2010 Nov 11.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验