Department of Otorhinolaryngology-Head and Neck Surgery, Helsinki University Hospital and University of Helsinki, PO Box 263, 00029 HUS, Helsinki, Finland.
Terveystalo Occupational Healthcare Services, Leppavaara and Espoontori, Espoo, Finland.
Eur Arch Otorhinolaryngol. 2020 Apr;277(4):1235-1245. doi: 10.1007/s00405-020-05817-y. Epub 2020 Jan 25.
To explore the characteristics, medical treatments, and long-term facial palsy outcome in Ramsay Hunt syndrome.
Patient questionnaire including self-assessment of long-term facial palsy outcome and retrospective chart review. Initial facial palsy grade was compared to self-assessed or patient record stated palsy outcome. Occurrence of different characteristics (blisters, hearing loss, vertigo, etc.) of the syndrome were assessed.
Altogether 120 patients were included of which 81 answered the questionnaire. All but one patient had received virus medication (aciclovir, valaciclovir), and half received simultaneous corticosteroids. If the medication was started within 72 h of Ramsay Hunt diagnosis, facial palsy recovered totally or with only slight sequelae in over 80% of the patients. Only a minority of the patients experienced varicella blisters simultaneously with facial palsy, blisters more often preceded or followed the palsy. Approximately 20% of the patients had their blisters in hidden places in the ear canal or mouth.
The long-term outcome of facial palsy in medically treated Ramsay Hunt syndrome was approaching the outcome of Bell's palsy. It is crucial to ask and inform the patient about the blisters and look for them since, more often than not, the blisters precede or follow the palsy and can be in areas not easily seen.
探讨 Ramsay Hunt 综合征的特点、治疗方法及长期面瘫结局。
采用患者问卷调查,包括面瘫长期结局的自我评估和回顾性病历审查。比较初始面瘫分级与自我评估或患者记录的面瘫结局。评估综合征的不同特征(水疱、听力损失、眩晕等)的发生情况。
共纳入 120 例患者,其中 81 例回答了问卷。除 1 例患者外,所有患者均接受了病毒药物(阿昔洛韦、伐昔洛韦)治疗,半数患者同时接受了皮质类固醇治疗。如果在 Ramsay Hunt 综合征诊断后 72 小时内开始用药,超过 80%的患者面瘫完全或仅有轻微后遗症恢复。仅有少数患者同时出现水痘样水疱和面瘫,水疱更常见于面瘫之前或之后。约 20%的患者耳内或口腔的水疱位于隐蔽部位。
经药物治疗的 Ramsay Hunt 综合征的面瘫长期结局接近贝尔面瘫。询问并告知患者有关水疱的情况并寻找水疱非常重要,因为水疱通常先于或后于面瘫出现,而且可能位于不易看到的部位。