Otolaryngology Department, University Hospital of Modena, Via del Pozzo 71, 41100 Modena, Italy.
Neurosci Res. 2012 Sep;74(1):7-9. doi: 10.1016/j.neures.2012.06.001. Epub 2012 Jun 16.
Reactivation of the varicella-zoster virus (VZV) along the sensory nerves innervating the ear, including the geniculate ganglion, is responsible for herpes zoster oticus (HZO). In some cases, HZO is associated with polyneuropathy of the cranial nerves, although the mechanism of this involvement is not known. To explain this phenomenon and based on some clinical considerations, the present authors hypothesize an intersynaptic spread of VZV along the reflex pathways of the brainstem.
水痘-带状疱疹病毒(VZV)沿着感觉神经重新激活,包括膝状神经节,是引起耳带状疱疹(HZO)的原因。在某些情况下,HZO 与颅神经多发性神经病有关,尽管其发病机制尚不清楚。为了解释这一现象,并基于一些临床考虑,本文作者假设 VZV 通过脑干反射通路的突触间传播。