Clinical Assistant Professor, Department of Orthodontics, Institute of Oral Health Science, Ajou University School of Medicine, Suwon, Republic of Korea.
Clinical Assistant Professor, Department of Oral and Maxillofacial Radiology, Seoul National University Dental Hospital, Seoul, Republic of Korea.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jun;129(6):629-634. doi: 10.1016/j.oooo.2019.11.006. Epub 2019 Nov 14.
The aim of this study was to analyze and compare the imaging features of osteomyelitis according to the presence or absence of antiresorptive medications by using computed tomography (CT).
We retrospectively reviewed the records of 270 patients with osteomyelitis (83 males and 187 females; average age 66.6 years). CT imaging features were analyzed, and imaging and demographic features were compared between the medication-related osteomyelitis (MROM) group and the medication-unrelated osteomyelitis (MUOM) group.
Trabecular defects, cortical defects, sclerosis, and sequestra were detected in the majority of patients, whereas periosteal new bone formation was less common. The MROM group exhibited sequestra and periosteal new bone formation more frequently on CT images, but the size and appearance of the sequestra and type of periosteal new bone were not significantly different between the 2 groups.
Sequestra and periosteal new bone formation were characteristic CT features of osteomyelitis more commonly found in the medication-related condition. These findings may be useful in the evaluation of osteomyelitis and medication-related osteonecrosis of the jaw.
本研究旨在通过使用计算机断层扫描（CT）分析和比较抗吸收药物存在或不存在时骨髓炎的影像学特征。
我们回顾性分析了 270 例骨髓炎患者（83 名男性和 187 名女性；平均年龄 66.6 岁）的记录。分析了 CT 成像特征，并比较了药物相关骨髓炎（MROM）组和药物无关骨髓炎（MUOM）组的影像学和人口统计学特征。
大多数患者存在骨小梁缺损、皮质缺损、硬化和死骨，而骨膜新骨形成较少见。MROM 组 CT 图像上更常见死骨和骨膜新骨形成，但 2 组的死骨大小和外观以及骨膜新骨类型无明显差异。
死骨和骨膜新骨形成是骨髓炎的特征性 CT 表现，在药物相关骨髓炎中更常见。这些发现可能有助于评估骨髓炎和药物相关性颌骨坏死。
