Asai Tetsuo, Usui Masaru, Sugiyama Michiyo, Izumi Kazuhiro, Ikeda Tomoyuki, Andoh Masako
The United Graduate School of Veterinary Medicine, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan.
School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi, Bunkyodai, Ebetsu, Hokkaido 069-8501, Japan.
J Vet Med Sci. 2020 Mar 24;82(3):345-349. doi: 10.1292/jvms.19-0554. Epub 2020 Jan 24.
The emergence and prevalence of antimicrobial-resistant bacteria in wild animals are a great concern for public health. A total of 963 Escherichia coli isolates from 475 wild mammals (242 sika deers, 112 wild boars, 113 small mammals, 4 Japanese badger, 2 Tokara cows, and 2 Amani rabbits), collected between 2013 and 2017, were examined for antimicrobial susceptibility. Resistance to at least one antimicrobial was observed in 92 of 963 isolates (9.3%). No isolates exhibited resistance to carbapenem (meropenem). Resistance to third-generation cephalosporin (cefotaxime) and fluoroquinolone (ciprofloxacin) was observed in less than 1% of the isolates. Thus, low prevalence of bacterial antimicrobial resistance was observed in wild mammals between 2013 and 2017 in Japan.
野生动物体内出现和流行的抗菌药物耐药菌是公共卫生领域极为关注的问题。对2013年至2017年间采集的475只野生哺乳动物（242只梅花鹿、112只野猪、113只小型哺乳动物、4只日本獾、2只德之岛牛和2只奄美兔）身上分离出的963株大肠杆菌进行了药敏试验。963株分离菌中有92株（9.3%）对至少一种抗菌药物耐药。没有分离菌对碳青霉烯类（美罗培南）耐药。对第三代头孢菌素（头孢噻肟）和氟喹诺酮类（环丙沙星）耐药的分离菌不到1%。因此，2013年至2017年间在日本野生哺乳动物中观察到细菌抗菌药物耐药性的流行率较低。
