2013年至2017年期间在日本从野生哺乳动物身上分离出的大肠杆菌菌株的抗菌药敏性。
Antimicrobial susceptibility of Escherichia coli isolates obtained from wild mammals between 2013 and 2017 in Japan.
作者信息
Asai Tetsuo, Usui Masaru, Sugiyama Michiyo, Izumi Kazuhiro, Ikeda Tomoyuki, Andoh Masako
机构信息
The United Graduate School of Veterinary Medicine, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan.
School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi, Bunkyodai, Ebetsu, Hokkaido 069-8501, Japan.
出版信息
J Vet Med Sci. 2020 Mar 24;82(3):345-349. doi: 10.1292/jvms.19-0554. Epub 2020 Jan 24.
Abstract
The emergence and prevalence of antimicrobial-resistant bacteria in wild animals are a great concern for public health. A total of 963 Escherichia coli isolates from 475 wild mammals (242 sika deers, 112 wild boars, 113 small mammals, 4 Japanese badger, 2 Tokara cows, and 2 Amani rabbits), collected between 2013 and 2017, were examined for antimicrobial susceptibility. Resistance to at least one antimicrobial was observed in 92 of 963 isolates (9.3%). No isolates exhibited resistance to carbapenem (meropenem). Resistance to third-generation cephalosporin (cefotaxime) and fluoroquinolone (ciprofloxacin) was observed in less than 1% of the isolates. Thus, low prevalence of bacterial antimicrobial resistance was observed in wild mammals between 2013 and 2017 in Japan.
摘要
野生动物体内出现和流行的抗菌药物耐药菌是公共卫生领域极为关注的问题。对2013年至2017年间采集的475只野生哺乳动物（242只梅花鹿、112只野猪、113只小型哺乳动物、4只日本獾、2只德之岛牛和2只奄美兔）身上分离出的963株大肠杆菌进行了药敏试验。963株分离菌中有92株（9.3%）对至少一种抗菌药物耐药。没有分离菌对碳青霉烯类（美罗培南）耐药。对第三代头孢菌素（头孢噻肟）和氟喹诺酮类（环丙沙星）耐药的分离菌不到1%。因此，2013年至2017年间在日本野生哺乳动物中观察到细菌抗菌药物耐药性的流行率较低。
相似文献
1
Antimicrobial susceptibility of Escherichia coli isolates obtained from wild mammals between 2013 and 2017 in Japan.2013年至2017年期间在日本从野生哺乳动物身上分离出的大肠杆菌菌株的抗菌药敏性。
J Vet Med Sci. 2020 Mar 24;82(3):345-349. doi: 10.1292/jvms.19-0554. Epub 2020 Jan 24.
2
Antimicrobial-resistant faecal Escherichia coli in wild mammals in central Europe: multiresistant Escherichia coli producing extended-spectrum beta-lactamases in wild boars.中欧野生哺乳动物中的抗微生物耐药粪便大肠杆菌：产生超广谱β-内酰胺酶的抗药性大肠杆菌在野猪中。
J Appl Microbiol. 2010 May;108(5):1702-11. doi: 10.1111/j.1365-2672.2009.04572.x. Epub 2009 Sep 30.
3
Antimicrobial resistance in generic Escherichia coli isolates from wild small mammals living in swine farm, residential, landfill, and natural environments in southern Ontario, Canada.安替比林耐药性在加拿大安大略省南部的养猪场、居民区、垃圾填埋场和自然环境中生活的野生小型哺乳动物的普通大肠杆菌分离株中的表现。
Appl Environ Microbiol. 2011 Feb;77(3):882-8. doi: 10.1128/AEM.01111-10. Epub 2010 Dec 3.
4
Genetic characteristics and antimicrobial resistance of Escherichia coli from Japanese macaques (Macaca fuscata) in rural Japan.日本农村地区日本猕猴（猕猴属fuscata）源大肠杆菌的遗传特征及抗菌药物耐药性
J Wildl Dis. 2011 Apr;47(2):261-70. doi: 10.7589/0090-3558-47.2.261.
5
First insights into antimicrobial resistance among faecal Escherichia coli isolates from small wild mammals in rural areas.农村地区小型野生动物粪便中产 ESBL 大肠埃希菌的耐药情况的初步研究。
Sci Total Environ. 2010 Aug 1;408(17):3519-22. doi: 10.1016/j.scitotenv.2010.05.005. Epub 2010 May 31.
6
Antimicrobial resistance in Escherichia coli isolates from swine and wild small mammals in the proximity of swine farms and in natural environments in Ontario, Canada.加拿大安大略省养猪场附近及自然环境中猪和野生小型哺乳动物源大肠杆菌的抗菌药物耐药性
Appl Environ Microbiol. 2009 Feb;75(3):559-66. doi: 10.1128/AEM.01821-08. Epub 2008 Dec 1.
7
Interspecies transmission of antimicrobial-resistant bacteria between wild birds and mammals in urban environment.城市环境中野生鸟类和哺乳动物之间的抗菌药物耐药菌的种间传播。
Vet Microbiol. 2024 Jul;294:110130. doi: 10.1016/j.vetmic.2024.110130. Epub 2024 May 29.
8
A survey of antimicrobial-resistant Escherichia coli prevalence in wild mammals in Japan using antimicrobial-containing media.使用含抗菌药物的培养基对日本野生哺乳动物中抗微生物药物耐药大肠杆菌流行率的调查。
J Vet Med Sci. 2022 Dec 14;84(12):1645-1652. doi: 10.1292/jvms.22-0415. Epub 2022 Oct 31.
9
Study of the spread of antimicrobial-resistant Enterobacteriaceae from wild mammals in the National Park of Aspromonte (Calabria, Italy).研究阿斯普罗蒙特国家公园（意大利卡拉布里亚）野生哺乳动物中抗微生物耐药肠杆菌科的传播。
Environ Toxicol Pharmacol. 2018 Oct;63:69-73. doi: 10.1016/j.etap.2018.08.016. Epub 2018 Aug 28.
10
Antimicrobial Resistance in Escherichia coli Isolated from Wild Animals in Poland.从波兰野生动物中分离出的大肠杆菌的抗微生物药物耐药性
Microb Drug Resist. 2018 Jul/Aug;24(6):807-815. doi: 10.1089/mdr.2017.0148. Epub 2017 Nov 29.
引用本文的文献
1
Antimicrobial Resistance in from Hedgehogs () Admitted to a Wildlife Rescue Center.来自野生动物救助中心收治的刺猬（）的抗菌药物耐药性
Animals (Basel). 2025 Jul 27;15(15):2206. doi: 10.3390/ani15152206.
2
Molecular Characterization of Multidrug-Resistant from Fecal Samples of Wild Animals.野生动物粪便样本中多重耐药菌的分子特征分析
Vet Sci. 2024 Oct 1;11(10):469. doi: 10.3390/vetsci11100469.
3
Characterization of quinolone-resistant and extended-spectrum β-lactamase-producing Escherichia coli derived from sika deer populations of the Nara Prefecture, Japan.日本奈良县梅花鹿种群中分离出的耐喹诺酮类和产生超广谱β-内酰胺酶的大肠杆菌的特性研究。
J Vet Med Sci. 2023 Sep 1;85(9):937-941. doi: 10.1292/jvms.23-0069. Epub 2023 Jul 12.
4
Evidence of Antimicrobial Resistance in Bats and Its Planetary Health Impact for Surveillance of Zoonotic Spillover Events: A Scoping Review.蝙蝠中的抗微生物药物耐药证据及其对监测人畜共患病溢出事件的行星健康影响：范围综述。
Int J Environ Res Public Health. 2022 Dec 23;20(1):243. doi: 10.3390/ijerph20010243.
5
Isolation of extended-spectrum β-lactamase-producing Escherichia coli from Japanese red fox (Vulpes vulpes japonica).从日本红狐（Vulpes vulpes japonica）中分离产超广谱β-内酰胺酶的大肠杆菌。
Microbiologyopen. 2022 Oct;11(5):e1317. doi: 10.1002/mbo3.1317.
6
A survey of antimicrobial-resistant Escherichia coli prevalence in wild mammals in Japan using antimicrobial-containing media.使用含抗菌药物的培养基对日本野生哺乳动物中抗微生物药物耐药大肠杆菌流行率的调查。
J Vet Med Sci. 2022 Dec 14;84(12):1645-1652. doi: 10.1292/jvms.22-0415. Epub 2022 Oct 31.
7
Current status and future perspective of antimicrobial-resistant bacteria and resistance genes in animal-breeding environments.动物养殖环境中抗微生物药物耐药菌和耐药基因的现状和未来展望。
J Vet Med Sci. 2022 Sep 12;84(9):1292-1298. doi: 10.1292/jvms.22-0253. Epub 2022 Jul 22.
8
Whole-genome sequence analysis of Shiga toxin-producing Escherichia coli O157 strains isolated from wild deer and boar in Japan.日本野生鹿和野猪中分离的产志贺毒素大肠杆菌 O157 菌株的全基因组序列分析。
J Vet Med Sci. 2021 Dec 2;83(12):1860-1868. doi: 10.1292/jvms.21-0454. Epub 2021 Oct 8.
9
Prevalence of antimicrobial resistance in bacteria isolated from Great Cormorants (Phalacrocorax carbo hanedae) in Japan.日本苍鹭（Phalacrocorax carbo hanedae）分离细菌的抗菌药物耐药性流行情况。
J Vet Med Sci. 2021 Aug 6;83(8):1191-1195. doi: 10.1292/jvms.21-0108. Epub 2021 Jun 9.
10
Association between the -harboring Isolated from Weasels and Domestic Animals Reared on a University Campus.从校园内饲养的鼬类和家畜中分离出的携带-的菌株之间的关联。 （你提供的原文中“-harboring”部分表述不完整，推测应该是有具体的某种物质或特征等，这里只能根据现有内容尽量准确翻译）
Antibiotics (Basel). 2021 Apr 13;10(4):432. doi: 10.3390/antibiotics10040432.
本文引用的文献
1
Prevalence of antimicrobial-resistant Escherichia coli in endangered Okinawa rail (Gallirallus okinawae) inhabiting areas around a livestock farm.在畜牧场周边濒危冲绳秧鸡（Gallirallus okinawae）栖息地中耐抗菌药物大肠杆菌的流行情况。
Vet Med Sci. 2019 Nov;5(4):563-568. doi: 10.1002/vms3.194. Epub 2019 Aug 26.
2
Antimicrobial resistance in faecal Escherichia coli isolates from farmed red deer and wild small mammals. Detection of a multiresistant E. coli producing extended-spectrum beta-lactamase.养殖马鹿和野生小型哺乳动物粪便中大肠杆菌分离株的抗菌药物耐药性。产超广谱β-内酰胺酶多重耐药大肠杆菌的检测。
Comp Immunol Microbiol Infect Dis. 2016 Apr;45:34-9. doi: 10.1016/j.cimid.2016.02.003. Epub 2016 Feb 18.
3
Long-Term Colonization by bla(CTX-M)-Harboring Escherichia coli in Healthy Japanese People Engaged in Food Handling.携带bla(CTX-M)的大肠杆菌在从事食品处理的健康日本人中的长期定植
Appl Environ Microbiol. 2016 Jan 8;82(6):1818-1827. doi: 10.1128/AEM.02929-15.
4
Analysis of molecular epidemiologic characteristics of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli colonizing feces in hospital patients and community dwellers in a Japanese city.日本某城市医院患者和社区居民粪便中产超广谱β-内酰胺酶（ESBL）大肠埃希菌的分子流行病学特征分析
J Infect Chemother. 2016 Feb;22(2):102-7. doi: 10.1016/j.jiac.2015.11.001. Epub 2015 Dec 17.
5
The Role of Flies in Disseminating Plasmids with Antimicrobial-Resistance Genes Between Farms.苍蝇在农场间传播携带抗微生物耐药基因质粒中的作用。
Microb Drug Resist. 2015 Oct;21(5):562-9. doi: 10.1089/mdr.2015.0033. Epub 2015 May 20.
6
Assessment of antibiotic resistance of Escherichia coli isolates and screening of Salmonella spp. in wild ungulates from Portugal.葡萄牙野生有蹄类动物中大肠杆菌分离株的抗生素耐药性评估及沙门氏菌属筛查。
Res Microbiol. 2015 Sep;166(7):584-93. doi: 10.1016/j.resmic.2015.03.006. Epub 2015 Apr 11.
7
Azorean wild rabbits as reservoirs of antimicrobial resistant Escherichia coli.亚速尔群岛野兔作为耐抗菌药大肠杆菌的宿主
Anaerobe. 2014 Dec;30:116-9. doi: 10.1016/j.anaerobe.2014.09.009. Epub 2014 Sep 20.
8
Antimicrobial resistant bacteria in wild mammals and birds: a coincidence or cause for concern?野生哺乳动物和鸟类中的抗微生物耐药细菌：巧合还是值得关注的原因？
Ir Vet J. 2014 Apr 25;67(1):8. doi: 10.1186/2046-0481-67-8. eCollection 2014.
9
Diversity of plasmid replicons encoding the bla(CMY-2) gene in broad-spectrum cephalosporin-resistant Escherichia coli from livestock animals in Japan.日本家畜动物中广谱头孢菌素耐药大肠杆菌携带 bla(CMY-2) 基因的质粒复制子多样性。
Foodborne Pathog Dis. 2013 Mar;10(3):243-9. doi: 10.1089/fpd.2012.1306.
10
Extended-Spectrum Beta-Lactamases Producing E. coli in Wildlife, yet Another Form of Environmental Pollution?野生动物中产生超广谱β-内酰胺酶的大肠杆菌，这是环境污染的另一种形式？
Front Microbiol. 2011 Dec 19;2:246. doi: 10.3389/fmicb.2011.00246. eCollection 2011.
Zotero 插件