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碘海醇及其他非离子介质中的红细胞聚集

Erythrocyte aggregation in iohexol and other nonionic media.

作者信息

Zucker M B, Mauss E A

机构信息

Department of Pathology, New York University Medical Center, NY 10016.

出版信息

Invest Radiol. 1988 Nov;23 Suppl 2:S340-5. doi: 10.1097/00004424-198811002-00006.

DOI:10.1097/00004424-198811002-00006
PMID:3198377
Abstract

Erythrocytes aggregate when blood comes into contact with solutions of nonionic substances such as glucose or the contrast medium iohexol, especially at a reduced pH (eg, 6.8). The aggregates are not clots because they form rapidly even in heparinized blood, do not contain fibrin, and disappear at once when they are added to plasma or other ionic media. Formation of these aggregates in solutions of glucose or iohexol can be decreased by including a low concentration of an ionic solute such as NaCl or by maintaining the pH close to 7.4.

摘要

当血液与非离子物质溶液(如葡萄糖或造影剂碘海醇)接触时,红细胞会发生聚集,尤其是在pH值降低(如6.8)的情况下。这些聚集体不是凝块,因为即使在肝素化血液中它们也能迅速形成,不含纤维蛋白,并且当它们加入血浆或其他离子介质中时会立即消失。在葡萄糖或碘海醇溶液中,通过加入低浓度的离子溶质(如氯化钠)或保持pH值接近7.4,可以减少这些聚集体的形成。

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