Robredo Irene Gaile C.
J Drugs Dermatol. 2020 Jan 1;19(1):66-69. doi: 10.36849/JDD.2020.4623.
Axillary post inflammatory hyperpigmentation (PIH) is one of the most common dermatological complaint in women with darker skin types. Standard of care include mainly topical bleaching agents either alone or combination with other treatments. Lately, laser-based treatments have emerged as potential therapeutic options for the treatment of PIH in patients with darker skin types. OBJECTIVE: To assess the safety and efficacy of a 1064 nm Q-switched Nd:YAG laser in the treatment of axillary hyperpigmentation in Filipino women with Fitzpatrick skin types IV-V. Materials and Methods: Nine women (18 axillae) ages 20-52 years old with axillary PIH were prospectively evaluated for treatment using a nanosecond 1064 nm Q-switched Nd:YAG laser. Clinical evaluation included pigmentary changes of PIH lesion compared to non-affected regions and GIAS satisfaction assessment both by the treating physician and patients. Safety parameters included adverse events and pain visual analogue scale (VAS) scoring. RESULTS: All axillae responded to the laser treatment, exhibiting reduction in pigmentation in 85-100% of lesion area. GIAS satisfaction results exhibited 22-33% excellent improvement and 55% much improved scores. All patients’ pigmentary improvements were maintained at the final follow-up visit, three months following final treatment. No adverse events were recorded throughout the trial. Treatment related pain was well tolerated, as exhibited by pain VAS scores recorded after each treatment. CONCLUSION: Use of a low-fluence 1064 nm Q-switched Nd:YAG laser in the treatment of axillary hyperpigmentation is safe and effective in patients with darker skin type. J Drugs Dermatol. 2020;19(1):66-69. doi:10.36849/JDD.2020.4623
腋窝部炎症后色素沉着（PIH）是深色皮肤类型女性中最常见的皮肤科问题之一。护理标准主要包括单独使用外用漂白剂或与其他治疗方法联合使用。最近，基于激光的治疗方法已成为治疗深色皮肤类型患者PIH的潜在治疗选择。
评估1064 nm调Q Nd:YAG激光治疗菲律宾IV-V型 Fitzpatrick皮肤类型女性腋窝色素沉着的安全性和有效性。
对9名年龄在20-52岁、患有腋窝PIH的女性（18个腋窝）进行前瞻性评估，使用纳秒级1064 nm调Q Nd:YAG激光进行治疗。临床评估包括PIH病变与未受影响区域相比的色素变化，以及治疗医生和患者的全球改善评估量表（GIAS）满意度评估。安全参数包括不良事件和疼痛视觉模拟量表（VAS）评分。
所有腋窝对激光治疗均有反应，85%-100%的病变区域色素沉着减少。GIAS满意度结果显示，22%-33%为极佳改善，55%为改善很多。所有患者的色素改善在最后一次治疗后三个月的最终随访中得以维持。整个试验期间未记录到不良事件。每次治疗后记录的疼痛VAS评分显示，治疗相关疼痛耐受性良好。
低能量1064 nm调Q Nd:YAG激光治疗深色皮肤类型患者的腋窝色素沉着是安全有效的。《药物皮肤病学杂志》。2020年；19(1):66-69。doi:10.36849/JDD.2020.4623
