Nisticò Steven Paul, Cannarozzo Giovanni, Provenzano Eugenio, Tamburi Federica, Fazia Gilda, Sannino Mario, Negosanti Francesca, Del Duca Ester, Patruno Cataldo, Bennardo Luigi
Department of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Unit of Dermatology, Tor Vergata University, 00133 Rome, Italy.
Clin Pract. 2021 Sep 23;11(4):708-714. doi: 10.3390/clinpract11040086.
(1) Benign hyperpigmentations are a common problem in cosmetic dermatology. Melasma, solar lentigo, and other acquired hyperpigmentations represent an aesthetic issue for an increasing number of patients. The gold standard in managing this condition is currently 1064/532 nanometers (nm) Q-Switched lasers. This study reports our experience on the use of a Q-switched laser with a nanosecond pulse to treat these conditions. (2) Methods: A total of 96 patients asking for benign hyperpigmentation removal were consecutively enrolled at the Magna Graecia University of Catanzaro and Tor Vergata University of Rome. Treating parameters were the following: 1064 nm with a pulse duration of 6 nanoseconds (ns) for dermic lesions and 532 nm with 6 ns for epidermal ones. Up to five treatments with a minimum interval between laser treatments of thirty days were performed. A follow-up visit three months after the last session assessed patient satisfaction with a Visual Analogue Scale (VAS). Two blinded dermatologists assessed the cosmetic result using a five-point scale comparing pictures before treatment and at follow-up. (3) Results: 96 patients were included; 47 participants were women (49.0%) and 49 men (51.0%). The mean reported age was 50.0 ± 17.3 years. All patients reached a good to complete hyperpigmentation removal at the dermatological evaluation with a mean VAS score of 8.91 ± 1.07. (4) Conclusions: Q Switched 1064/532 nm laser may be considered the gold standard treatment for benign hyperpigmentations. Our results confirm the literature findings on the effectiveness of these devices.
（1）良性色素沉着是皮肤美容领域的常见问题。黄褐斑、日光性雀斑样痣以及其他后天性色素沉着给越来越多的患者带来了美观问题。目前，治疗这种情况的金标准是1064/532纳米（nm）调Q激光。本研究报告了我们使用纳秒脉冲调Q激光治疗这些病症的经验。（2）方法：共有96名要求去除良性色素沉着的患者相继在卡坦扎罗的大希腊大学和罗马的托尔韦尔加塔大学入组。治疗参数如下：对于真皮层病变，采用波长1064 nm、脉冲持续时间6纳秒（ns）的激光；对于表皮层病变，采用波长532 nm、6 ns的激光。最多进行5次治疗，激光治疗之间的最短间隔为30天。在最后一次治疗后三个月进行随访，使用视觉模拟量表（VAS）评估患者满意度。两名不知情的皮肤科医生使用五点量表通过比较治疗前和随访时的照片来评估美容效果。（3）结果：纳入96名患者；47名参与者为女性（49.0%），49名男性（51.0%）。报告的平均年龄为50.0±17.3岁。在皮肤科评估中，所有患者的色素沉着均得到良好至完全清除，平均VAS评分为8.91±1.07。（4）结论：1064/532 nm调Q激光可被视为良性色素沉着的金标准治疗方法。我们的结果证实了文献中关于这些设备有效性的研究结果。
