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川崎病抗凝治疗前胃肠道出血:病例报告。

Gastrointestinal hemorrhage before anticoagulant therapy in Kawasaki disease: a case report.

机构信息

Department of Pediatrics, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.

出版信息

BMC Pediatr. 2020 Jan 27;20(1):32. doi: 10.1186/s12887-020-1916-6.

Abstract

BACKGROUND

Kawasaki disease (KD) is an acute febrile multisystem vasculitis and has been recognized to be the most common cause of acquired heart disease in children. Owing to its propensity to involve vessels throughout the entire body, KD often mimics other disease processes. The diagnosis might be delayed if other prominent symptoms appear before the characteristic clinical features of KD. Although gastrointestinal symptoms including vomiting, diarrhea, and abdominal pain are not uncommon in KD patients, KD with gastrointestinal bleeding is quite rare.

CASE PRESENTATION

A previously healthy 4-year-old boy initially presented with abdominal pain, followed by fever, rash, and gastrointestinal hemorrhage, eventually diagnosed as complete KD. The patient recovered smoothly after appropriate management and no subsequent complications occurred in the following months.

CONCLUSION

The diagnosis of KD should be considered in children presenting with abdominal symptoms and fever without definable cause. Pediatricians should be aware of the risk of gastrointestinal bleeding in patients with KD, especially in those with prominent abdominal symptoms.

摘要

背景

川崎病(KD)是一种急性发热性全身性血管炎,已被认为是儿童获得性心脏病的最常见原因。由于其倾向于累及全身的血管,KD 经常模仿其他疾病过程。如果其他突出症状在 KD 的典型临床特征之前出现,可能会延误诊断。尽管胃肠道症状包括呕吐、腹泻和腹痛在 KD 患者中并不罕见,但 KD 伴胃肠道出血却相当罕见。

病例介绍

一名既往健康的 4 岁男孩最初表现为腹痛,随后出现发热、皮疹和胃肠道出血,最终被诊断为完全型 KD。经过适当的治疗,该患者病情平稳恢复,随后数月内未出现其他并发症。

结论

对于出现腹部症状和不明原因发热的儿童,应考虑 KD 的诊断。儿科医生应该意识到 KD 患者,特别是伴有明显腹部症状的患者,存在胃肠道出血的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eff1/6983962/fd7d21648171/12887_2020_1916_Fig1_HTML.jpg

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