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Assessing plasminogen activation potential with global fibrinolytic assays.

作者信息

Urano Tetsumei, Suzuki Yuko

机构信息

Hamamatsu University School of Medicine-Medical Physiology Hamamatsu Shizuoka Japan.

出版信息

Res Pract Thromb Haemost. 2019 Dec 26;4(1):13-15. doi: 10.1002/rth2.12293. eCollection 2020 Jan.

DOI:10.1002/rth2.12293
PMID:31989079
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6971321/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e36/6971321/7b185e469ed9/RTH2-4-13-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e36/6971321/7b185e469ed9/RTH2-4-13-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e36/6971321/7b185e469ed9/RTH2-4-13-g001.jpg

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A rare coding mutation in the MAST2 gene causes venous thrombosis in a French family with unexplained thrombophilia: The Breizh MAST2 Arg89Gln variant.一个罕见的 MAST2 基因突变导致一个法国家族性不明原因血栓形成伴静脉血栓形成:Breizh MAST2 Arg89Gln 变异体。
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本文引用的文献

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Development and application of global assays of hyper- and hypofibrinolysis.高纤溶和低纤溶整体检测方法的开发与应用。
Res Pract Thromb Haemost. 2019 Nov 6;4(1):46-53. doi: 10.1002/rth2.12275. eCollection 2020 Jan.
2
Recognition of Plasminogen Activator Inhibitor Type 1 as the Primary Regulator of Fibrinolysis.认识到纤溶酶原激活物抑制剂1是纤维蛋白溶解的主要调节因子。
Curr Drug Targets. 2019;20(16):1695-1701. doi: 10.2174/1389450120666190715102510.
3
Regulation of plasminogen activation on cell surfaces and fibrin.细胞表面和纤维蛋白上纤溶酶原激活的调节
J Thromb Haemost. 2018 May 20;16(8):1487-97. doi: 10.1111/jth.14157.
4
Mutation in a highly conserved glycine residue in strand 5B of plasminogen activator inhibitor 1 causes polymerisation.纤溶酶原激活物抑制剂1第5B链中一个高度保守的甘氨酸残基发生突变会导致聚合反应。
Thromb Haemost. 2017 May 3;117(5):860-869. doi: 10.1160/TH16-07-0572. Epub 2017 Feb 23.
5
Disseminated intravascular coagulation.弥散性血管内凝血。
Nat Rev Dis Primers. 2016 Jun 2;2:16037. doi: 10.1038/nrdp.2016.37.
6
Life-threatening hemorrhage and prolonged wound healing are remarkable phenotypes manifested by complete plasminogen activator inhibitor-1 deficiency in humans.危及生命的出血和伤口愈合延长是人类完全缺乏纤溶酶原激活物抑制剂-1所表现出的显著表型。
J Thromb Haemost. 2011 Jun;9(6):1200-6. doi: 10.1111/j.1538-7836.2011.04288.x.
7
New insights into the molecular mechanisms of the fibrinolytic system.纤溶系统分子机制的新见解。
J Thromb Haemost. 2009 Jan;7(1):4-13. doi: 10.1111/j.1538-7836.2008.03220.x. Epub 2008 Nov 8.
8
Discovery of alpha2-plasmin inhibitor and its congenital deficiency.α2-纤溶酶抑制剂的发现及其先天性缺乏症。
J Thromb Haemost. 2005 Apr;3(4):623-31. doi: 10.1111/j.1538-7836.2004.01055.x.
9
Plasminogen activator inhibitor-1, inflammation, obesity, insulin resistance and vascular risk.纤溶酶原激活物抑制剂-1、炎症、肥胖、胰岛素抵抗与血管风险
J Thromb Haemost. 2003 Jul;1(7):1575-9. doi: 10.1046/j.1538-7836.2003.00279.x.
10
The expression of exercise-induced tPA activity in blood is regulated by the basal level of PAI-1.
Thromb Haemost. 2001 Apr;85(4):751-2.