College of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China.
Shandong Key Laboratory of Coastal Environmental Processes, CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.
Analyst. 2020 Mar 2;145(5):1943-1949. doi: 10.1039/c9an02575h.
A facile and novel method was developed to improve the conductivity of a cyclodextrin-metal organic frameworks (CD-MOFs) by modifying it with Ketjen Black (KB) and platinum nanoparticles (PtNPs). The structural morphology and composition of this PtNPs/KB/CD-MOFs nanocomposite was characterized by transmission electron microscopy, scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, elemental mapping, and Raman spectroscopy. The sensor was then evaluated for its ability to detect ofloxacin using cyclic voltammetry, and the results showed that the PtNPs/KB/CD-MOF had high sensitivity, satisfactory stability and good reproducibility. In addition, a great linear range was obtained with a concentration range of 0.08-100 μM and a low detection limit of 0.037 μM (S/N = 3). Therefore, the prepared electrochemical sensor could be successfully used to detect ofloxacin in serum.
开发了一种简便新颖的方法，通过用 Ketjen Black（KB）和铂纳米粒子（PtNPs）修饰它来提高环糊精-金属有机骨架（CD-MOFs）的电导率。通过透射电子显微镜、扫描电子显微镜、傅里叶变换红外光谱、X 射线光电子能谱、元素映射和拉曼光谱对 PtNPs/KB/CD-MOFs 纳米复合材料的结构形态和组成进行了表征。然后使用循环伏安法评估了传感器对氧氟沙星的检测能力，结果表明 PtNPs/KB/CD-MOF 具有高灵敏度、令人满意的稳定性和良好的重现性。此外，还获得了一个大的线性范围，浓度范围为 0.08-100 μM，检测限低至 0.037 μM（S/N = 3）。因此，所制备的电化学传感器可成功用于检测血清中的氧氟沙星。
