Medical College of Wisconsin, Milwaukee, WI.
Department of Dermatology (Pediatric Dermatology) and Pediatrics, Medical College of Wisconsin, Milwaukee, WI.
Pediatr Dermatol. 2020 Mar;37(2):317-319. doi: 10.1111/pde.14103. Epub 2020 Jan 28.
BACKGROUND/OBJECTIVES: Calcinosis cutis is the abnormal deposition of calcium in the skin and subcutis. There is currently a paucity of data surrounding pediatric calcinosis cutis. The objective of this study is to characterize calcinosis cutis in a pediatric cohort.
A single-institution retrospective cohort study was performed over a 5.5-year period.
Thirty cases were identified. Calcinosis cutis was found to be more common in men (63%), with a younger median age of onset (5 years) compared to women (10 years). Dystrophic calcinosis cutis (43%) was the most common type in the study population, though idiopathic calcinosis cutis (37%) was nearly as common. No cases of metastatic calcinosis cutis were found.
The etiology of calcinosis cutis in the study population was found to be similar to that identified in adults with the exception of metastatic calcinosis cutis, which was not seen in our cohort. Previous recommendations using laboratory testing to diagnose this disease process might not be as critical as previously thought.
背景/目的：皮肤和皮下组织内钙异常沉积称为钙沉积症。目前有关儿童钙沉积症的数据较少。本研究旨在对儿科钙沉积症患者的临床特征进行描述。
本研究为回顾性单中心队列研究，研究时间为 5.5 年。
共纳入 30 例患者。钙沉积症男性患者（63%）更为常见，发病中位年龄（5 岁）较女性患者（10 岁）更早。营养不良性钙沉积症（43%）是本研究中最常见的类型，而特发性钙沉积症（37%）则较为常见。未发现转移性钙沉积症。
与成人钙沉积症的病因相似，但本研究人群中未发现转移性钙沉积症。既往建议通过实验室检查来诊断钙沉积症，但可能不如之前认为的那么重要。
