Department of Pediatric Cardiology, Chiba Children's Hospital, Chiba.
Department of Pediatric Cardiology, Hokkaido Medical Center for Child Health and Rehabilitation.
J Hypertens. 2020 May;38(5):813-820. doi: 10.1097/HJH.0000000000002360.
Central blood pressure (CBP) can now be reliably measured noninvasively with a number of devices in adult; however, noninvasive assessment of CBP has not been validated in children and adolescents. The purpose of this study was to clarify the accuracy of noninvasive oscillometric CBP measurements in children and adolescents.
This study included 60 patients with an average age of 7.9 ± 4.4 years (range 1-18 years) who underwent a cardiac catheterization. We compared CBP, estimated with a noninvasive oscillometric method using a Mobil-O-Graph, with simultaneous invasive recordings using a catheter in children and adolescents.
Comparison of the SBP values measured by the two methods, showing a linear correlation (r = 0.85; P < 0.0001) with the mean difference aortic SBP minus estimated central SBP of 2.0 ± 5.6 mmHg (95% limits of agreement = -9.0-13.1). In DBP values, there was a correlation (r = 0.72; P < 0.0001) with the mean difference aortic DBP minus estimated central DBP of -0.1 ± 6.4 mmHg (95% limits of agreement = -12.6-12.4). Sex and cardiac function did not affect central SBP estimation; however, the correlation between aortic and estimated central SBP in adolescents was better than that in children (r = 0.93, P < 0.0001 vs. r = 0.77, P < 0.0001), though the difference was not statistically significant (P = 0.483).
Estimated CBP using Mobil-O-Graph in children and adolescents shows a certain degree of accuracy, which will be helpful in future for evaluating CBP in children and adolescents.
目前已有多种设备可无创测量中心血压(CBP),并在成人中得到可靠应用;然而,CBP 的无创评估尚未在儿童和青少年中得到验证。本研究旨在明确非侵入性振荡法测量儿童和青少年 CBP 的准确性。
本研究纳入了 60 例平均年龄为 7.9±4.4 岁(1-18 岁)的患者,他们均接受了心导管检查。我们比较了使用 Mobil-O-Graph 进行的非侵入性振荡法测量的 CBP 与使用导管进行的同步有创记录的 CBP。
两种方法测量的收缩压值具有线性相关性(r=0.85;P<0.0001),平均差值为主动脉收缩压减去估计的中心收缩压 2.0±5.6mmHg(95%置信区间为-9.0-13.1)。在舒张压值方面,也具有相关性(r=0.72;P<0.0001),平均差值为主动脉舒张压减去估计的中心舒张压-0.1±6.4mmHg(95%置信区间为-12.6-12.4)。性别和心功能均不影响中心收缩压的估计;然而,青少年主动脉与估计中心收缩压的相关性优于儿童(r=0.93,P<0.0001 与 r=0.77,P<0.0001),尽管差异无统计学意义(P=0.483)。
Mobil-O-Graph 用于儿童和青少年的估计 CBP 具有一定的准确性,这将有助于未来评估儿童和青少年的 CBP。