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基于脉搏波分析的西印度某城市成年人主动脉血压与肱动脉血压标准下高血压患病率的比较研究

Comparison of Prevalent Hypertension by Aortic versus Brachial Blood Pressure Criteria for - A Pulse Wave Analysis Based Study from Adults of a City of West India.

作者信息

Solanki Jayesh D, Sajan Pearl K, Trivedi Bansi J, Kakadia Param J, Panjwani Sunil J, Mohandas Krishnapriya

机构信息

Department of Physiology, Government Medical College, Bhavnagar, India.

Government Medical College, Bhavnagar, India.

出版信息

Niger Med J. 2025 Apr 3;66(1):109-116. doi: 10.71480/nmj.v66i1.616. eCollection 2025 Jan-Feb.

Abstract

BACKGROUND

Disparities exist in aortic blood pressure (aBP) and brachial blood pressure (bBP) and between aortic (AH) versus brachial hypertension (BH). While the former is superior, it is studied scarcely. Pulse wave analysis (PWA) provides objective and simultaneous measurement of both blood pressures to determine AH and BH. Using PWA, we compared prevalent AH and BH in a sample adult population.

METHODOLOGY

By oscillometric PWA (Mobilograph, IEM, Stolberg, Germany), 1187 participants with age >18 years were evaluated. Simultaneous aBP and bBP were recorded by standard PWA protocol and prevalence of AH and BH was estimated. Age and gender-based subgroups were compared for aortic versus brachial BP differences. Prevalence of Hypertension, Isolated Systolic Hypertension, and Pulse Pressure ≥40 was compared between aortic versus brachial criteria.

RESULTS

Significant differences were seen between bBP and aBP across all age groups and in both genders, especially for the younger age groups. As compared to bBP, aBP gave a higher fetch for prevalent hypertension and a lower fetch for prevalent Isolated Systolic Hypertension (ISH). bPP ≥40 was sensitive but not specific as a surrogate for aPP ≥ 40.

CONCLUSION

Across ages 18-65 in either sex, disparities exist between bBP and aBP mostly for SBP and PP with significant differences in prevalent Hypertension, Isolated Systemic Hypertension, and high pulse pressure. It reaffirms disparities of aBP and bBP and diagnosed brachial or central hypertension based on them with the need for further work.

摘要

背景

主动脉血压(aBP)与肱动脉血压(bBP)之间以及主动脉高血压(AH)与肱动脉高血压(BH)之间存在差异。虽然前者更具优势,但对其研究甚少。脉搏波分析(PWA)可同时客观测量两种血压,以确定AH和BH。我们使用PWA比较了成年人群样本中AH和BH的患病率。

方法

通过示波法PWA(德国斯托尔伯格IEM公司的Mobilograph)对1187名年龄大于18岁的参与者进行评估。按照标准PWA方案记录同步的aBP和bBP,并估算AH和BH的患病率。比较基于年龄和性别的亚组之间主动脉血压与肱动脉血压的差异。比较主动脉标准与肱动脉标准之间高血压、单纯收缩期高血压和脉压≥40的患病率。

结果

在所有年龄组和男女两性中,bBP和aBP之间均存在显著差异,尤其是在较年轻的年龄组中。与bBP相比,aBP对高血压患病率的检出率更高,对单纯收缩期高血压(ISH)患病率的检出率更低。bPP≥40作为aPP≥40的替代指标具有敏感性,但不具有特异性。

结论

在18至65岁的任何性别中,bBP和aBP之间存在差异,主要体现在收缩压(SBP)和脉压(PP)方面,在高血压、单纯系统性高血压和高脉压的患病率上存在显著差异。这再次证实了aBP和bBP之间的差异,以及基于它们诊断肱动脉或中枢性高血压的差异,需要进一步开展工作。

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