原发性甲状旁腺功能亢进伴广泛棕色瘤及肱骨远端骨折——病例报告
Primary hyperparathyroidism with extensive brown tumours and distal humerus fracture-A case report.
作者信息
Kumar Yadav Amit, Pawar Eknath, Harsoor Abhishek, Kumar G S Prasanna, Rohra Hitesh
机构信息
Grant Medical College & Sir JJ Group of Hospitals Mumbai, India.
Grant Medical College & Sir JJ Group of Hospitals Mumbai, India.
出版信息
Int J Surg Case Rep. 2020;66:421-424. doi: 10.1016/j.ijscr.2019.12.042. Epub 2020 Jan 16.
INTRODUCTION
A brown tumour is benign bony lesion caused by localized, rapid osteoclastic turnover, resulting from hyperparathyroidism. In this report, we present a case of 25-year-old woman with multiple swelling and bone pain. Plain radiographs of the affected bones revealed multiple erosive bone tumours, which were diagnosed as brown tumours associated with primary hyperparathyroidism.
CASE REPORT
A 25 year old female presented with swelling in left elbow since 1 month along with multiple swelling in body. Patient had pain in left elbow after trivial fall. X-ray showed lytic lesion of left elbow with pathological fracture. Biopsy was suggestive of brown tumour of distal humerus.
DISCUSSION
We managed this case with reconstruction of defect with fibula grafting and plating.
CONCLUSION
Pathological fracture in young adult should always be properly investigated. A high index of suspicion is necessary to diagnose unusual presentation of Primary Hyperparathyroidism.
引言
棕色瘤是一种由甲状旁腺功能亢进引起的局限性、快速破骨细胞转换导致的良性骨病变。在本报告中，我们介绍了一名25岁女性，她有多处肿胀和骨痛。受累骨骼的X线平片显示多处侵蚀性骨肿瘤，被诊断为与原发性甲状旁腺功能亢进相关的棕色瘤。
病例报告
一名25岁女性自1个月前出现左肘部肿胀，身体多处也有肿胀。患者在轻微跌倒后左肘部疼痛。X线显示左肘部溶骨性病变伴病理性骨折。活检提示肱骨远端棕色瘤。
讨论
我们采用腓骨移植和钢板内固定修复缺损的方法治疗该病例。
结论
对于年轻成年人的病理性骨折，应始终进行适当的检查。高度怀疑对于诊断原发性甲状旁腺功能亢进的不寻常表现是必要的。
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