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牙买加阿开木(Blighia sapida)中皂苷作为牙膏中月桂醇硫酸酯钠替代品的潜力。

The potential of saponin from Jamaica's Blighia sapida (ackee) as a substitute for sodium lauryl sulphate in toothpaste.

作者信息

Paul Tomlin J, Taylor Tanielle A, Rajendra Santosh Arvind Babu

机构信息

Faculty of Medical Sciences, The University of the West Indies, Mona, Jamaica.

Department of Community Health and Psychiatry, Faculty of Medical Sciences, The University of the West Indies, Mona, Jamaica.

出版信息

Med Hypotheses. 2020 Apr;137:109555. doi: 10.1016/j.mehy.2020.109555. Epub 2020 Jan 7.

Abstract

Discovering novel means of protection from harmful substances in toothpaste is essential due to its mass production, and frequent exposure to its ingredients by consumers. This method of safeguarding through discovery demonstrates toothpaste safety, which is at risk of being stifled by other commercial priorities. Among the ingredients in toothpaste that cause adverse effects is sodium lauryl sulphate (SLS). An understanding of this source and its effects therefore allows for investigating preventative strategies through the use of safer alternatives. Saponin, a naturally occurring chemical in several plant species was discovered to be an alternative compound that may parallel the effects of sodium lauryl sulphate, yet exude less ill effects. This article highlights the benefits of saponin and its presence in a heavily consumed and exported fruit in Jamaica (ackee, Blighia sapida). The possibility of extracting saponin from ackee, and its use in the toothpaste industry as an alternative to sodium lauryl sulphate are discussed. Through consideration of this alternative, the potential exists to improve the safety of toothpastes and consequently improve oral health.

摘要

由于牙膏的大规模生产以及消费者频繁接触其成分,发现保护牙齿免受牙膏中有害物质侵害的新方法至关重要。这种通过发现来保障安全的方法体现了牙膏的安全性,而牙膏安全性有被其他商业优先事项抑制的风险。牙膏中会产生不良影响的成分之一是月桂醇硫酸酯钠(SLS)。因此,了解该成分来源及其影响有助于通过使用更安全的替代品来研究预防策略。皂角苷是几种植物中天然存在的化学物质,被发现是一种替代化合物,其效果可能与月桂醇硫酸酯钠相当,但不良影响较小。本文强调了皂角苷的益处及其在牙买加一种大量消费和出口的水果(阿开木,Blighia sapida)中的存在。讨论了从阿开木中提取皂角苷并将其用于牙膏行业以替代月桂醇硫酸酯钠的可能性。通过考虑这种替代品,存在改善牙膏安全性并进而改善口腔健康的潜力。

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