Anwar Mohamed A, Sayed Ghadir A, Hal Dina M, Hafeez Mohamed S Abd El, Shatat Abdel-Aziz S, Salman Aya, Eisa Nehal M, Ramadan Asmaa, El-Shiekh Riham A, Hatem Shymaa, Aly Shaza H
Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.
Department of Biochemistry, Faculty of Pharmacy, Egyptian Russian University, Badr, Cairo, 11829, Egypt.
Inflammopharmacology. 2025 Mar;33(3):1085-1160. doi: 10.1007/s10787-024-01631-8. Epub 2025 Feb 5.
Across diverse cultures, herbal remedies have been used to alleviate oral discomfort and maintain dental hygiene. This review presents studies on herbal remedies with remarkable antimicrobial, anti-inflammatory, antioxidant, anticancer, anticaries, analgesic, and healing properties. The manuscripts demonstrate the depth of scientific inquiry into herbal remedies used for the management of various oral and dental health conditions. These include gingivitis, oral ulcers, mucositis, periodontitis, oral pathogens, carcinoma, xerostomia, and dental caries. Researchers have investigated the phytochemical and pharmacological properties of plant-derived compounds and their extracts evaluated their interactions with oral pathogens and inflammatory processes. The convergence of traditional knowledge and rigorous scientific investigation offers a compelling narrative, fostering a deeper understanding of herbal remedies as viable alternatives to conventional dental interventions. This work has the potential to provide patients with access to gentle, yet effective solutions, and simultaneously offer dental health professionals the opportunity to enrich their knowledge, and ability to provide personalized, holistic care. This review highlights the symbiotic relationship between herbal medicine and scientific understanding, emphasizing the importance of disseminating this knowledge to benefit both practitioners and patients, enabling evidence-based decision-making in dental care. The exploration of herbal remedies offers a promising alternative, potentially mitigating some of these side effects while promoting oral health in a more natural and holistic manner.
在不同文化中，草药已被用于缓解口腔不适和保持口腔卫生。本综述介绍了有关具有显著抗菌、抗炎、抗氧化、抗癌、防龋、止痛和愈合特性的草药的研究。这些手稿展示了对用于管理各种口腔和牙齿健康状况的草药进行科学探究的深度。这些状况包括牙龈炎、口腔溃疡、黏膜炎、牙周炎、口腔病原体、癌症、口干症和龋齿。研究人员研究了植物衍生化合物及其提取物的植物化学和药理特性，评估了它们与口腔病原体和炎症过程的相互作用。传统知识与严谨科学研究的融合提供了一个引人入胜的叙述，促进了对草药作为传统牙科干预可行替代方案的更深入理解。这项工作有可能为患者提供温和但有效的解决方案，同时为牙科保健专业人员提供丰富其知识和提供个性化整体护理能力的机会。本综述强调了草药医学与科学理解之间的共生关系，强调传播这些知识对从业者和患者都有益的重要性，从而在牙科护理中实现基于证据的决策。对草药的探索提供了一个有前景的替代方案，有可能减轻一些这些副作用，同时以更自然和整体的方式促进口腔健康。
