Cesare Marincola Flaminia, Mannina Luisa
Dipartimento di Scienze Chimiche e Geologiche, Cittadella Universitaria di Monserrato, Università di Cagliari, SS 554, Monserrato 09042, Italy.
Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma, P.le Aldo Moro 5, Rome 00185, Italy.
Metabolites. 2020 Jan 26;10(2):45. doi: 10.3390/metabo10020045.
Over the last decade, the number of scientific publications in the metabolomics area has increased exponentially. The literature includes ~29,000 contributions (articles and reviews) during the period of 2009-2019, revealing metabolomics applications in a wide range of fields, including medical, plant, animal, and food sciences (this bibliographic data were retrieved from the SCOPUS database, searching "metabolomics" in keywords). The high applicability of this approach is due to its ability to qualitatively and quantitatively characterize the chemical profile of all the low molecular weight metabolites (metabolome) present in cells, tissues, organs, and biological fluids as end products of the cellular regulatory pathways. Thus, providing a snapshot of the phenotype of a biological system, metabolomics offers useful contributions to a comprehensive insight into the functional status of human, animal, plant, and microbe organisms. The contributions collected in this Special Issue (12 articles, one review and one technical report) report on the recent technical advances and practical applications of NMR spectroscopy to metabolomics analyses.
在过去十年中，代谢组学领域的科学出版物数量呈指数级增长。文献中包括2009年至2019年期间约29000篇文献（文章和综述），揭示了代谢组学在广泛领域的应用，包括医学、植物、动物和食品科学（这些文献数据是从SCOPUS数据库检索的，在关键词中搜索“代谢组学”）。这种方法的高度适用性源于其能够定性和定量地表征细胞、组织、器官和生物流体中作为细胞调节途径终产物存在的所有低分子量代谢物（代谢组）的化学特征。因此，代谢组学提供了生物系统表型的快照，为全面洞察人类、动物、植物和微生物的功能状态做出了有益贡献。本期特刊收集的文献（12篇文章、1篇综述和1篇技术报告）报道了核磁共振波谱在代谢组学分析中的最新技术进展和实际应用。
