作为白内障手术并发症的出血性闭塞性视网膜血管炎的早期抗血管内皮生长因子治疗
Early anti-VEGF treatment for hemorrhagic occlusive retinal vasculitis as a complication of cataract surgery.
作者信息
Andreanos Konstantinos, Petrou Petros, Kymionis George, Papaconstantinou Dimitrios, Georgalas Ilias
机构信息
First Division of Ophthalmology, School of Medicine, National and Kapodistrian University of Athens, "G. Gennimatas" General Hospital of Athens, Athens, Greece.
, 22str Digeni E.O.K.A, Nea Penteli, 15236, Athens, Greece.
出版信息
BMC Ophthalmol. 2017 Dec 6;17(1):238. doi: 10.1186/s12886-017-0632-y.
BACKGROUND
We report a case of hemorrhagic occlusive retinal vasculitis (HORV) after prophylactic intracameral vancomycin use during an uneventful cataract surgery treated with early anti-VEGF treatment.
CASE PRESENTATION
A 51-year-old female underwent uneventful cataract surgery with prophylactic intracameral vancomycin during the procedure. On the seventh post-operative-day, she presented with sudden painful, visual loss. Fundus examination revealed peripheral hemorrhagic retinal vasculitis. She received anti-VEGF therapy to prevent further vision loss and retinal neovascularization due to extensive retinal ischemia. At the 6-month follow-up visit, visual acuity was 20/20 with no sign of neovascularization.
CONCLUSIONS
Postoperative HORV is a devastating condition that can occur after otherwise uncomplicated cataract surgery. The nature of this rare condition remains unknown. Early anti-VEGF administration seems to demonstrate favorable results.
背景
我们报告一例在白内障手术过程中预防性前房内使用万古霉素后发生出血性闭塞性视网膜血管炎（HORV）的病例，该病例通过早期抗血管内皮生长因子（VEGF）治疗。
病例介绍
一名51岁女性在手术过程中接受了预防性前房内使用万古霉素的白内障手术，手术过程顺利。术后第七天，她突然出现疼痛性视力丧失。眼底检查发现周边部出血性视网膜血管炎。她接受了抗VEGF治疗，以防止因广泛的视网膜缺血导致进一步的视力丧失和视网膜新生血管形成。在6个月的随访中，视力为20/20，无新生血管形成迹象。
结论
术后HORV是一种破坏性疾病，可发生在原本无并发症的白内障手术后。这种罕见疾病的性质尚不清楚。早期给予抗VEGF似乎显示出良好的效果。
Zotero 插件