Hubei Collaborative Innovation Centre for Advanced Organic Chemical Materials and Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei University, Wuhan 430062, People's Republic of China.
Biomater Sci. 2020 Mar 17;8(6):1502-1535. doi: 10.1039/c9bm01729a.
Surface wettability plays an important role in regulating biomolecule adhesion behaviors. The biomolecule adhesion behaviors of superwettable surfaces have become an important topic as an important part of the interactions between materials and organisms. In addition to general research on the moderate wettability of surfaces, the studies of biomolecule adhesion behaviors extend to extreme wettability ranges such as superhydrophobic, superhydrophilic and slippery surfaces and attract both fundamental and practical interest. In this review, we summarize the recent studies on biomolecule adhesion behaviors on superwettable surfaces, especially superhydrophobic, superhydrophilic and slippery surfaces. The first part will focus on the influence of extreme wettability on cell adhesion behaviors. The second part will concentrate on the adhesion behaviors of biomacromolecules on superwettable surfaces including proteins and nucleic acids. Finally, the influences of wettability on small molecule adhesion behaviors on material surfaces have also been investigated. The mechanism of superwettable surfaces and their influences on biomolecule adhesion behaviors have been studied and highlighted.
表面润湿性在调节生物分子黏附行为方面起着重要作用。超润湿性表面的生物分子黏附行为已成为材料与生物体相互作用的重要组成部分，成为一个重要的研究课题。除了对表面适度润湿性的一般研究外，生物分子黏附行为的研究还扩展到超疏水、超亲水和滑润表面等极端润湿性范围，引起了基础研究和实际应用的兴趣。本综述总结了近年来关于超润湿性表面上生物分子黏附行为的研究进展，特别是超疏水、超亲水和滑润表面。第一部分将重点讨论极端润湿性对细胞黏附行为的影响。第二部分将集中研究生物大分子（包括蛋白质和核酸）在超润湿性表面上的黏附行为。最后，还研究了润湿性对材料表面小分子黏附行为的影响。对超润湿性表面的作用机制及其对生物分子黏附行为的影响进行了研究和强调。
