Universidade Federal do Rio de Janeiro, Faculdade de Medicina, Departamento de Oftalmologia, Rio de Janeiro, RJ, Brasil.
Rev Soc Bras Med Trop. 2020 Jan 27;53:e20190160. doi: 10.1590/0037-8682-0160-2019. eCollection 2020.
Acute disseminated encephalomyelitis (ADEM) is a demyelinating autoimmune neuropathic condition characterized by extensive bilateral and confluent lesions in the cerebral white matter and cerebellum. The basal ganglia and gray matter may also be involved. In most cases, the symptoms are preceded by viral infection or vaccination. In this report, we present a case of ADEM associated with optic neuritis presenting alongside two potential triggering factors: chikungunya virus infection and yellow fever immunization.
急性播散性脑脊髓炎(ADEM)是一种脱髓鞘自身免疫性神经病变,其特征是大脑白质和小脑广泛双侧融合性病变。基底节和灰质也可能受累。在大多数情况下,症状在前病毒感染或疫苗接种之后出现。在本报告中,我们介绍了一例伴有视神经炎的 ADEM 病例,同时存在两个潜在的触发因素:基孔肯雅病毒感染和黄热病免疫接种。