用于甲状旁腺功能障碍小鼠中磷酸盐和碱性磷酸酶原位检测的荧光纳米传感器。
Fluorescent nanosensor for in situ detection of phosphate and alkaline phosphatase in mice with parathyroid dysfunction.
机构信息
College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Institute of Biomedical Sciences, Shandong Normal University, Jinan 250014, P. R. China.
出版信息
Chem Commun (Camb). 2020 Feb 25;56(16):2431-2434. doi: 10.1039/c9cc08828h.
A composite nanosensor based on Zr(iv)-MOFs and PNPP was developed, and was successfully applied for the in situ fluorescence imaging of phosphate and ALP levels in mice with parathyroid dysfunction. The current work provides new ideas for further development of the diagnosis of parathyroid diseases.
基于 Zr(iv)-MOFs 和 PNPP 开发了一种复合纳米传感器，并成功应用于甲状旁腺功能障碍小鼠中磷酸盐和 ALP 水平的荧光成像。本工作为甲状旁腺疾病的诊断提供了新的思路。
Zotero 插件