Peat George, Rathod-Mistry Trishna, Paskins Zoe, Marshall Michelle, Thomas Martin J, Menz Hylton B, Nicholls Elaine, Myers Helen, Duncan Rachel, van der Windt Danielle A, Roddy Ed, Dziedzic Krysia S
Primary Care Centre Versus Arthritis, School of Primary, Community, and Social Care, Keele University, UK.
Keele Clinical Trials Unit, Keele University, Staffordshire, UK.
Musculoskeletal Care. 2020 Jun;18(2):219-224. doi: 10.1002/msc.1457. Epub 2020 Jan 29.
In this brief report, we used data from a series of three related cohorts on pain and osteoarthritis (OA) of the knee, hand and foot, which were conducted in North Staffordshire, England. We used a common approach for sampling, data collection and coding, to estimate the relative prevalence of 10 different symptomatic radiographic OA subtypes in the knee, hand and foot and to compare their association with age, sex, socioeconomic position and body mass index. Overall, symptomatic hand OA was more common than knee or foot OA (22.4% vs 17.4% vs 16.5%), due mainly to the high prevalence of nodal interphalangeal joint OA among women. The first carpometacarpal joint OA was the most frequent subtype, with patellofemoral, tibiofemoral, (nodal) interphalangeal and midfoot OA also common. Of the risk factors examined, the greatest differences between subtypes appeared to be their associations with sex and obesity: sex differences were noticeably greater for all forms of hand OA except non-nodal interphalangeal joint OA, while obesity appeared most strongly associated with forms of knee OA. The prevalence of all subtypes was higher among older ages, and among those with lower educational attainment.
在本简要报告中，我们使用了来自英格兰北斯塔福德郡的一系列三个相关队列的数据，这些队列涉及膝、手和足的疼痛与骨关节炎（OA）。我们采用了一种通用的抽样、数据收集和编码方法，以估计膝、手和足中10种不同症状性放射学OA亚型的相对患病率，并比较它们与年龄、性别、社会经济地位和体重指数的关联。总体而言，有症状的手部OA比膝部或足部OA更常见（分别为22.4%、17.4%和16.5%），这主要是由于女性指间关节OA的患病率较高。第一腕掌关节OA是最常见的亚型，髌股关节、胫股关节、（结节性）指间关节和中足OA也较为常见。在所研究的风险因素中，各亚型之间最大的差异似乎在于它们与性别和肥胖的关联：除非结节性指间关节OA外，所有形式的手部OA的性别差异都更为明显，而肥胖似乎与膝部OA的形式关联最为密切。所有亚型的患病率在老年人以及教育程度较低者中更高。
